Shu X - Search Results

1

Enhancement of gemcitabine efficacy by K73-03 via epigenetically regulation of miR-421/SPINK1 in gemcitabine resistant pancreatic cancer cells.

Shopit A, Li X, Wang S, Awsh M, Safi M, Chu P, Jia J, Al-Radhi M, Baldi S, Wang F, Fang J, Peng J, Ma X, Tang Z, Shu X. Shopit A, et al. Among authors: shu x. Phytomedicine. 2021 Oct;91:153711. doi: 10.1016/j.phymed.2021.153711. Epub 2021 Aug 18. Phytomedicine. 2021. PMID: 34450377

2

Novel Quinazoline Derivatives Bearing Various 4-Aniline Moieties as Potent EGFR Inhibitors with Enhanced Activity Against NSCLC Cell Lines.

Wang C, Sun Y, Zhu X, Wu B, Wang Q, Zhen Y, Shu X, Liu K, Zhou Y, Ma X. Wang C, et al. Among authors: shu x. Chem Biol Drug Des. 2016 Apr;87(4):635-43. doi: 10.1111/cbdd.12692. Epub 2015 Dec 29. Chem Biol Drug Des. 2016. PMID: 26613384

3

Challenges and Perspectives on the Development of Small-Molecule EGFR Inhibitors against T790M-Mediated Resistance in Non-Small-Cell Lung Cancer.

Song Z, Ge Y, Wang C, Huang S, Shu X, Liu K, Zhou Y, Ma X. Song Z, et al. Among authors: shu x. J Med Chem. 2016 Jul 28;59(14):6580-94. doi: 10.1021/acs.jmedchem.5b00840. Epub 2016 Feb 26. J Med Chem. 2016. PMID: 26882288

4

Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.

Zhao D, Huang S, Qu M, Wang C, Liu Z, Li Z, Peng J, Liu K, Li Y, Ma X, Shu X. Zhao D, et al. Among authors: shu x. Eur J Med Chem. 2017 Jan 27;126:444-455. doi: 10.1016/j.ejmech.2016.11.047. Epub 2016 Nov 23. Eur J Med Chem. 2017. PMID: 27912175

5

Differential sensitivities of bladder cancer cell lines to resveratol are unrelated to its metabolic profile.

Yang Y, Li C, Li H, Wu M, Ren C, Zhen Y, Ma X, Diao Y, Ma X, Deng S, Liu J, Shu X. Yang Y, et al. Among authors: shu x. Oncotarget. 2017 Jun 20;8(25):40289-40304. doi: 10.18632/oncotarget.15041. Oncotarget. 2017. PMID: 28178690 Free PMC article.

6

Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the gefitinib-resistant non-small cell lung cancers (NSCLC).

Song Z, Huang S, Yu H, Jiang Y, Wang C, Meng Q, Shu X, Sun H, Liu K, Li Y, Ma X. Song Z, et al. Among authors: shu x. Eur J Med Chem. 2017 Jun 16;133:329-339. doi: 10.1016/j.ejmech.2017.03.083. Epub 2017 Apr 2. Eur J Med Chem. 2017. PMID: 28395219

7

Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

Liu H, Qu M, Xu L, Han X, Wang C, Shu X, Yao J, Liu K, Peng J, Li Y, Ma X. Liu H, et al. Among authors: shu x. Eur J Med Chem. 2017 Jul 28;135:60-69. doi: 10.1016/j.ejmech.2017.04.037. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28432946

8

Design, synthesis and biological evaluation of sulfonamide-substituted diphenylpyrimidine derivatives (Sul-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with antitumor activity.

Qu M, Liu Z, Zhao D, Wang C, Zhang J, Tang Z, Liu K, Shu X, Yuan H, Ma X. Qu M, et al. Among authors: shu x. Bioorg Med Chem. 2017 Aug 1;25(15):3989-3996. doi: 10.1016/j.bmc.2017.05.044. Epub 2017 May 20. Bioorg Med Chem. 2017. PMID: 28576633

9

Covalent binding design strategy: A prospective method for discovery of potent targeted anticancer agents.

Wang L, Zhao J, Yao Y, Wang C, Zhang J, Shu X, Sun X, Li Y, Liu K, Yuan H, Ma X. Wang L, et al. Among authors: shu x. Eur J Med Chem. 2017 Dec 15;142:493-505. doi: 10.1016/j.ejmech.2017.09.024. Epub 2017 Sep 20. Eur J Med Chem. 2017. PMID: 28986130 Review.

10

Therapeutic Versatility of Resveratrol Derivatives.

Nawaz W, Zhou Z, Deng S, Ma X, Ma X, Li C, Shu X. Nawaz W, et al. Among authors: shu x. Nutrients. 2017 Oct 29;9(11):1188. doi: 10.3390/nu9111188. Nutrients. 2017. PMID: 29109374 Free PMC article. Review.

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