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FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis.
Yakkundi A, Bennett R, Hernández-Negrete I, Delalande JM, Hanna M, Lyubomska O, Arthur K, Short A, McKeen H, Nelson L, McCrudden CM, McNally R, McClements L, McCarthy HO, Burns AJ, Bicknell R, Kissenpfennig A, Robson T. Yakkundi A, et al. Among authors: short a. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):845-54. doi: 10.1161/ATVBAHA.114.304539. Epub 2015 Mar 12. Arterioscler Thromb Vasc Biol. 2015. PMID: 25767277 Free PMC article.
FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4.
McClements L, Annett S, Yakkundi A, O'Rourke M, Valentine A, Moustafa N, Alqudah A, Simões BM, Furlong F, Short A, McIntosh SA, McCarthy HO, Clarke RB, Robson T. McClements L, et al. Among authors: short a. BMC Cancer. 2019 Apr 11;19(1):351. doi: 10.1186/s12885-019-5500-0. BMC Cancer. 2019. PMID: 30975104 Free PMC article.
DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen.
Cole G, Ali AA, McErlean E, Mulholland EJ, Short A, McCrudden CM, McCaffrey J, Robson T, Kett VL, Coulter JA, Dunne NJ, Donnelly RF, McCarthy HO. Cole G, et al. Among authors: short a. Acta Biomater. 2019 Sep 15;96:480-490. doi: 10.1016/j.actbio.2019.07.003. Epub 2019 Jul 9. Acta Biomater. 2019. PMID: 31299353
FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer.
Annett S, Moore G, Short A, Marshall A, McCrudden C, Yakkundi A, Das S, McCluggage WG, Nelson L, Harley I, Moustafa N, Kennedy CJ, deFazio A, Brand A, Sharma R, Brennan D, O'Toole S, O'Leary J, Bates M, O'Riain C, O'Connor D, Furlong F, McCarthy H, Kissenpfennig A, McClements L, Robson T. Annett S, et al. Among authors: short a. Br J Cancer. 2020 Feb;122(3):361-371. doi: 10.1038/s41416-019-0649-5. Epub 2019 Nov 27. Br J Cancer. 2020. PMID: 31772325 Free PMC article.
491 results