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Therapeutic targeting of hepatic ACSL4 ameliorates NASH in mice.
Duan J, Wang Z, Duan R, Yang C, Zhao R, Feng Q, Qin Y, Jiang J, Gu S, Lv K, Zhang L, He B, Birnbaumer L, Yang S, Chen Z, Yang Y. Duan J, et al. Among authors: jiang j. Hepatology. 2022 Jan;75(1):140-153. doi: 10.1002/hep.32148. Epub 2021 Nov 27. Hepatology. 2022. PMID: 34510514 Free PMC article.
Multispecies transcriptomics identifies SIKE as a MAPK repressor that prevents NASH progression.
Bai L, Qu W, Cheng X, Yang H, Huang YP, Wang Z, Han C, Tian RF, Hu F, Yang L, Tian S, Tian H, Cai Z, Wan J, Jiang J, Fu J, Zhou J, Hu Y, Ma T, Zhang X, Ji YX, Cai J, She ZG, Wang Y, Zhang P, Huang L, Li H, Zhang XJ. Bai L, et al. Among authors: jiang j. Sci Transl Med. 2024 Feb 14;16(734):eade7347. doi: 10.1126/scitranslmed.ade7347. Epub 2024 Feb 14. Sci Transl Med. 2024. PMID: 38354227
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