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Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Hajda J, Leuchs B, Angelova AL, Frehtman V, Rommelaere J, Mertens M, Pilz M, Kieser M, Krebs O, Dahm M, Huber B, Engeland CE, Mavratzas A, Hohmann N, Schreiber J, Jäger D, Halama N, Sedlaczek O, Gaida MM, Daniel V, Springfeld C, Ungerechts G. Hajda J, et al. Among authors: kieser m. Clin Cancer Res. 2021 Oct 15;27(20):5546-5556. doi: 10.1158/1078-0432.CCR-21-1020. Epub 2021 Aug 23. Clin Cancer Res. 2021. PMID: 34426438 Clinical Trial.
A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol.
Hajda J, Lehmann M, Krebs O, Kieser M, Geletneky K, Jäger D, Dahm M, Huber B, Schöning T, Sedlaczek O, Stenzinger A, Halama N, Daniel V, Leuchs B, Angelova A, Rommelaere J, Engeland CE, Springfeld C, Ungerechts G. Hajda J, et al. Among authors: kieser m. BMC Cancer. 2017 Aug 29;17(1):576. doi: 10.1186/s12885-017-3604-y. BMC Cancer. 2017. PMID: 28851316 Free PMC article. Clinical Trial.
A variational approach to optimal two-stage designs.
Pilz M, Kunzmann K, Herrmann C, Rauch G, Kieser M. Pilz M, et al. Among authors: kieser m. Stat Med. 2019 Sep 20;38(21):4159-4171. doi: 10.1002/sim.8291. Epub 2019 Jul 1. Stat Med. 2019. PMID: 31264243
Optimal planning of adaptive two-stage designs.
Pilz M, Kunzmann K, Herrmann C, Rauch G, Kieser M. Pilz M, et al. Among authors: kieser m. Stat Med. 2021 Jun 15;40(13):3196-3213. doi: 10.1002/sim.8953. Epub 2021 Mar 18. Stat Med. 2021. PMID: 33738842
311 results