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Phase 2 Trial of Oncolytic H-1 Parvovirus Therapy Shows Safety and Signs of Immune System Activation in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Hajda J, Leuchs B, Angelova AL, Frehtman V, Rommelaere J, Mertens M, Pilz M, Kieser M, Krebs O, Dahm M, Huber B, Engeland CE, Mavratzas A, Hohmann N, Schreiber J, Jäger D, Halama N, Sedlaczek O, Gaida MM, Daniel V, Springfeld C, Ungerechts G. Hajda J, et al. Among authors: angelova al. Clin Cancer Res. 2021 Oct 15;27(20):5546-5556. doi: 10.1158/1078-0432.CCR-21-1020. Epub 2021 Aug 23. Clin Cancer Res. 2021. PMID: 34426438 Clinical Trial.
Oncolytic parvoviruses as cancer therapeutics.
Rommelaere J, Geletneky K, Angelova AL, Daeffler L, Dinsart C, Kiprianova I, Schlehofer JR, Raykov Z. Rommelaere J, et al. Among authors: angelova al. Cytokine Growth Factor Rev. 2010 Apr-Jun;21(2-3):185-95. doi: 10.1016/j.cytogfr.2010.02.011. Epub 2010 Mar 7. Cytokine Growth Factor Rev. 2010. PMID: 20211577 Review.
Double-faceted mechanism of parvoviral oncosuppression.
Geletneky K, Nüesch JP, Angelova A, Kiprianova I, Rommelaere J. Geletneky K, et al. Curr Opin Virol. 2015 Aug;13:17-24. doi: 10.1016/j.coviro.2015.03.008. Epub 2015 Apr 2. Curr Opin Virol. 2015. PMID: 25841215 Review.
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