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Structural basis for microtubule binding and release by dynein.
Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE. Redwine WB, et al. Among authors: leschziner ae. Science. 2012 Sep 21;337(6101):1532-1536. doi: 10.1126/science.1224151. Science. 2012. PMID: 22997337 Free PMC article.
Mechanism and regulation of cytoplasmic dynein.
Cianfrocco MA, DeSantis ME, Leschziner AE, Reck-Peterson SL. Cianfrocco MA, et al. Among authors: leschziner ae. Annu Rev Cell Dev Biol. 2015;31:83-108. doi: 10.1146/annurev-cellbio-100814-125438. Epub 2015 Sep 30. Annu Rev Cell Dev Biol. 2015. PMID: 26436706 Free PMC article. Review.
Lis1 Has Two Opposing Modes of Regulating Cytoplasmic Dynein.
DeSantis ME, Cianfrocco MA, Htet ZM, Tran PT, Reck-Peterson SL, Leschziner AE. DeSantis ME, et al. Among authors: leschziner ae. Cell. 2017 Sep 7;170(6):1197-1208.e12. doi: 10.1016/j.cell.2017.08.037. Cell. 2017. PMID: 28886386 Free PMC article.
LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes.
Htet ZM, Gillies JP, Baker RW, Leschziner AE, DeSantis ME, Reck-Peterson SL. Htet ZM, et al. Among authors: leschziner ae. Nat Cell Biol. 2020 May;22(5):518-525. doi: 10.1038/s41556-020-0506-z. Epub 2020 Apr 27. Nat Cell Biol. 2020. PMID: 32341549 Free PMC article.
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE. Deniston CK, et al. Among authors: leschziner ae. Nature. 2020 Dec;588(7837):344-349. doi: 10.1038/s41586-020-2673-2. Epub 2020 Aug 19. Nature. 2020. PMID: 32814344 Free PMC article.
Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Gillies JP, Reimer JM, Karasmanis EP, Lahiri I, Htet ZM, Leschziner AE, Reck-Peterson SL. Gillies JP, et al. Among authors: leschziner ae. Elife. 2022 Jan 7;11:e71229. doi: 10.7554/eLife.71229. Elife. 2022. PMID: 34994688 Free PMC article.
53 results