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Page 1
Safety, bactericidal activity, and pharmacokinetics of the antituberculosis drug candidate BTZ-043 in South Africa (PanACEA-BTZ-043-02): an open-label, dose-expansion, randomised, controlled, phase 1b/2a trial.
Heinrich N, de Jager V, Dreisbach J, Gross-Demel P, Schultz S, Gerbach S, Kloss F, Dawson R, Narunsky K, Matt L, Wildner L, McHugh TD, Fuhr U, Aldana BH, Mouhdad C, Brake LT, Boeree MJ, Aarnoutse RE, Svensson EM, Gong X, P J Phillips P, Diacon AH, Hoelscher M; PanACEA-TB consortium. Heinrich N, et al. Among authors: aarnoutse re. Lancet Microbe. 2024 Dec 26:100952. doi: 10.1016/j.lanmic.2024.07.015. Online ahead of print. Lancet Microbe. 2024. PMID: 39793592 Free article.
Replacing rifampicin with minocycline increases the activity of the treatment regimen for Mycobacterium avium complex pulmonary disease in a dynamic hollow-fibre system.
Raaijmakers J, Ruth MM, Schildkraut JA, Hombergh EVD, Aarnoutse RE, Svensson EM, Wertheim HFL, Hoefsloot W, van Ingen J. Raaijmakers J, et al. Among authors: aarnoutse re. Int J Antimicrob Agents. 2024 Dec 27:107423. doi: 10.1016/j.ijantimicag.2024.107423. Online ahead of print. Int J Antimicrob Agents. 2024. PMID: 39734052 Free article.
Metagenomic analysis during capecitabine therapy reveals microbial chemoprotective mechanisms and predicts drug toxicity in colorectal cancer patients.
Hillege LE, Trepka KR, Ziemons J, Aarnoutse R, Guthrie BGH, de Vos-Geelen J, Valkenburg-van Iersel L, van Hellemond IEG, Baars A, Vestjens JHMJ, Penders J, Deutschbauer A, Atreya CE, Kidder WA, Turnbaugh PJ, Smidt ML. Hillege LE, et al. Among authors: aarnoutse r. medRxiv [Preprint]. 2024 Oct 15:2024.10.11.24315249. doi: 10.1101/2024.10.11.24315249. medRxiv. 2024. PMID: 39484258 Free PMC article. Preprint.
A loading dose of clofazimine to rapidly achieve steady-state-like concentrations in patients with nontuberculous mycobacterial disease.
Stemkens R, Lemson A, Koele SE, Svensson EM, Te Brake LHM, van Crevel R, Boeree MJ, Hoefsloot W, van Ingen J, Aarnoutse RE. Stemkens R, et al. Among authors: aarnoutse re. J Antimicrob Chemother. 2024 Dec 2;79(12):3100-3108. doi: 10.1093/jac/dkae309. J Antimicrob Chemother. 2024. PMID: 39378281 Free PMC article. Clinical Trial.
Advancing the chemotherapy of tuberculous meningitis: a consensus view.
Wasserman S, Donovan J, Kestelyn E, Watson JA, Aarnoutse RE, Barnacle JR, Boulware DR, Chow FC, Cresswell FV, Davis AG, Dooley KE, Figaji AA, Gibb DM, Huynh J, Imran D, Marais S, Meya DB, Misra UK, Modi M, Raberahona M, Ganiem AR, Rohlwink UK, Ruslami R, Seddon JA, Skolimowska KH, Solomons RS, Stek CJ, Thuong NTT, van Crevel R, Whitaker C, Thwaites GE, Wilkinson RJ. Wasserman S, et al. Among authors: aarnoutse re. Lancet Infect Dis. 2025 Jan;25(1):e47-e58. doi: 10.1016/S1473-3099(24)00512-7. Epub 2024 Sep 26. Lancet Infect Dis. 2025. PMID: 39342951 Free PMC article.
Influence of age and co-medication on dolutegravir glucuronidation in paediatric patients.
Jacobs TG, Waalewijn H, Houlden L, Bollen PDJ, Nanduudu A, Nambi E, Cassim H, Lugemwa A, Makumbi S, Monkiewicz LN, Shakeshaft C, Bamford A, Archary M, Musuro G, Chidziva E, Mujuru HA, Bwakura-Dangarembizi M, Chabala C, Turkova A, Gibb DM, Cotton MF, Aarnoutse R, Burger DM, Colbers A. Jacobs TG, et al. Among authors: aarnoutse r. Br J Clin Pharmacol. 2024 Nov;90(11):2947-2952. doi: 10.1111/bcp.16238. Epub 2024 Sep 3. Br J Clin Pharmacol. 2024. PMID: 39228168 Free PMC article.
Evaluation of a national multidisciplinary meeting for non-tuberculous mycobacterial disease.
Lemson A, Koster TA, Carpaij N, Magis-Escurra C, Boeree M, Stemkens R, Aarnoutse RE, van Laarhoven A, van Crevel R, van Ingen J, Hoefsloot W. Lemson A, et al. Among authors: aarnoutse re. IJTLD Open. 2024 Jun 1;1(6):279-281. doi: 10.5588/ijtldopen.24.0044. eCollection 2024 Jun. IJTLD Open. 2024. PMID: 39021452 Free PMC article. No abstract available.
The Effect of Real-Time Medication Monitoring-Based Digital Adherence Tools on Adherence to Antiretroviral Therapy and Viral Suppression in People Living With HIV: A Systematic Literature Review and Meta-Analysis.
Msosa TC, Swai I, Aarnoutse R, Rinke de Wit TF, Ngowi K, Msefula C, Nliwasa M, Boer MS. Msosa TC, et al. Among authors: aarnoutse r. J Acquir Immune Defic Syndr. 2024 Aug 15;96(5):411-420. doi: 10.1097/QAI.0000000000003449. Epub 2024 Jul 9. J Acquir Immune Defic Syndr. 2024. PMID: 38985562 Free PMC article.
253 results