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MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A. Kalogirou C, et al. Among authors: kubler h. Nat Commun. 2021 Aug 20;12(1):5066. doi: 10.1038/s41467-021-25325-9. Nat Commun. 2021. PMID: 34417456 Free PMC article.
High expression of Sterol-O-Acyl transferase 1 (SOAT1), an enzyme involved in cholesterol metabolism, is associated with earlier biochemical recurrence in high risk prostate cancer.
Eckhardt C, Sbiera I, Krebs M, Sbiera S, Spahn M, Kneitz B, Joniau S, Fassnacht M, Kübler H, Weigand I, Kroiss M. Eckhardt C, et al. Among authors: kubler h. Prostate Cancer Prostatic Dis. 2022 Sep;25(3):484-490. doi: 10.1038/s41391-021-00431-3. Epub 2021 Jul 29. Prostate Cancer Prostatic Dis. 2022. PMID: 34326474 Free PMC article.
miR-221 Augments TRAIL-Mediated Apoptosis in Prostate Cancer Cells by Inducing Endogenous TRAIL Expression and Targeting the Functional Repressors SOCS3 and PIK3R1.
Krebs M, Behrmann C, Kalogirou C, Sokolakis I, Kneitz S, Kruithof-de Julio M, Zoni E, Rech A, Schilling B, Kübler H, Spahn M, Kneitz B. Krebs M, et al. Among authors: kubler h. Biomed Res Int. 2019 Nov 14;2019:6392748. doi: 10.1155/2019/6392748. eCollection 2019. Biomed Res Int. 2019. PMID: 31828111 Free PMC article.
Reduced Segmentation of Lesions Is Comparable to Whole-Body Segmentation for Response Assessment by PSMA PET/CT: Initial Experience with the Keyhole Approach.
Hartrampf PE, Krebs M, Peter L, Heinrich M, Ruffing J, Kalogirou C, Weinke M, Brumberg J, Kübler H, Buck AK, Werner RA, Seitz AK. Hartrampf PE, et al. Among authors: kubler h. Biology (Basel). 2022 Apr 26;11(5):660. doi: 10.3390/biology11050660. Biology (Basel). 2022. PMID: 35625388 Free PMC article.
68Ga-PSMA I&T PET/CT for primary staging of prostate cancer.
Cytawa W, Seitz AK, Kircher S, Fukushima K, Tran-Gia J, Schirbel A, Bandurski T, Lass P, Krebs M, Połom W, Matuszewski M, Wester HJ, Buck AK, Kübler H, Lapa C. Cytawa W, et al. Among authors: kubler h. Eur J Nucl Med Mol Imaging. 2020 Jan;47(1):168-177. doi: 10.1007/s00259-019-04524-z. Epub 2019 Sep 16. Eur J Nucl Med Mol Imaging. 2020. PMID: 31529265
171 results