Gerwick WH - Search Results

1

Selective Neutral pH Inhibitor of Cathepsin B Designed Based on Cleavage Preferences at Cytosolic and Lysosomal pH Conditions.

Yoon MC, Solania A, Jiang Z, Christy MP, Podvin S, Mosier C, Lietz CB, Ito G, Gerwick WH, Wolan DW, Hook G, O'Donoghue AJ, Hook V. Yoon MC, et al. Among authors: gerwick wh. ACS Chem Biol. 2021 Sep 17;16(9):1628-1643. doi: 10.1021/acschembio.1c00138. Epub 2021 Aug 20. ACS Chem Biol. 2021. PMID: 34416110 Free PMC article.

2

An aldehyde-containing galactolipid from the red alga Gracilariopsis lemaneiformis.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. Lipids. 1991 Nov;26(11):960-3. doi: 10.1007/BF02535985. Lipids. 1991. PMID: 1805099

3

Novel pyrroles from the Oregon red alga Gracilariopsis lemaneiformis.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. J Nat Prod. 1991 Mar-Apr;54(2):403-7. doi: 10.1021/np50074a009. J Nat Prod. 1991. PMID: 1919587

4

Novel oxylipins from the temperate red alga Polyneura latissima: evidence for an arachidonate 9(S)-lipoxygenase.

Jiang ZD, Gerwick WH. Jiang ZD, et al. Among authors: gerwick wh. Lipids. 1997 Mar;32(3):231-5. doi: 10.1007/s11745-997-0029-9. Lipids. 1997. PMID: 9076659

5

The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L.

Miller B, Friedman AJ, Choi H, Hogan J, McCammon JA, Hook V, Gerwick WH. Miller B, et al. Among authors: gerwick wh. J Nat Prod. 2014 Jan 24;77(1):92-9. doi: 10.1021/np400727r. Epub 2013 Dec 23. J Nat Prod. 2014. PMID: 24364476 Free PMC article.

6

Microbiota of healthy corals are active against fungi in a light-dependent manner.

Moree WJ, McConnell OJ, Nguyen DD, Sanchez LM, Yang YL, Zhao X, Liu WT, Boudreau PD, Srinivasan J, Atencio L, Ballesteros J, Gavilán RG, Torres-Mendoza D, Guzmán HM, Gerwick WH, Gutiérrez M, Dorrestein PC. Moree WJ, et al. Among authors: gerwick wh. ACS Chem Biol. 2014 Oct 17;9(10):2300-8. doi: 10.1021/cb500432j. Epub 2014 Aug 6. ACS Chem Biol. 2014. PMID: 25058318 Free PMC article.

7

Domain Organization and Active Site Architecture of a Polyketide Synthase C-methyltransferase.

Skiba MA, Sikkema AP, Fiers WD, Gerwick WH, Sherman DH, Aldrich CC, Smith JL. Skiba MA, et al. Among authors: gerwick wh. ACS Chem Biol. 2016 Dec 16;11(12):3319-3327. doi: 10.1021/acschembio.6b00759. Epub 2016 Oct 18. ACS Chem Biol. 2016. PMID: 27723289 Free PMC article.

8

Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.

LaMonte GM, Almaliti J, Bibo-Verdugo B, Keller L, Zou BY, Yang J, Antonova-Koch Y, Orjuela-Sanchez P, Boyle CA, Vigil E, Wang L, Goldgof GM, Gerwick L, O'Donoghue AJ, Winzeler EA, Gerwick WH, Ottilie S. LaMonte GM, et al. Among authors: gerwick l, gerwick wh. J Med Chem. 2017 Aug 10;60(15):6721-6732. doi: 10.1021/acs.jmedchem.7b00671. Epub 2017 Jul 25. J Med Chem. 2017. PMID: 28696697 Free PMC article.

9

A Mononuclear Iron-Dependent Methyltransferase Catalyzes Initial Steps in Assembly of the Apratoxin A Polyketide Starter Unit.

Skiba MA, Sikkema AP, Moss NA, Tran CL, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. Among authors: gerwick l, gerwick wh. ACS Chem Biol. 2017 Dec 15;12(12):3039-3048. doi: 10.1021/acschembio.7b00746. Epub 2017 Nov 14. ACS Chem Biol. 2017. PMID: 29096064 Free PMC article.

10

Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module.

Skiba MA, Sikkema AP, Moss NA, Lowell AN, Su M, Sturgis RM, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Skiba MA, et al. Among authors: gerwick l, gerwick wh. ACS Chem Biol. 2018 Jun 15;13(6):1640-1650. doi: 10.1021/acschembio.8b00252. Epub 2018 May 8. ACS Chem Biol. 2018. PMID: 29701944 Free PMC article.

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