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Phase 1 study in healthy participants of the safety, pharmacokinetics, and pharmacodynamics of enpatoran (M5049), a dual antagonist of toll-like receptors 7 and 8.
Port A, Shaw JV, Klopp-Schulze L, Bytyqi A, Vetter C, Hussey E, Mammasse N, Ona V, Bachmann A, Strugala D, Reh C, Goteti K. Port A, et al. Among authors: klopp schulze l. Pharmacol Res Perspect. 2021 Oct;9(5):e00842. doi: 10.1002/prp2.842. Pharmacol Res Perspect. 2021. PMID: 34414672 Free PMC article. Clinical Trial.
Obesity Alters Endoxifen Plasma Levels in Young Breast Cancer Patients: A Pharmacometric Simulation Approach.
Mueller-Schoell A, Klopp-Schulze L, Schroth W, Mürdter T, Michelet R, Brauch H, Huisinga W, Joerger M, Neven P, Koolen SLW, Mathijssen RHJ, Copson E, Eccles D, Chen S, Chowbay B, Tfayli A, Zgheib NK, Schwab M, Kloft C. Mueller-Schoell A, et al. Among authors: klopp schulze l. Clin Pharmacol Ther. 2020 Sep;108(3):661-670. doi: 10.1002/cpt.1960. Epub 2020 Jul 23. Clin Pharmacol Ther. 2020. PMID: 32578187
Computational Treatment Simulations to Assess the Need for Personalized Tamoxifen Dosing in Breast Cancer Patients of Different Biogeographical Groups.
Mueller-Schoell A, Michelet R, Klopp-Schulze L, van Dyk M, Mürdter TE, Schwab M, Joerger M, Huisinga W, Mikus G, Kloft C. Mueller-Schoell A, et al. Among authors: klopp schulze l. Cancers (Basel). 2021 May 18;13(10):2432. doi: 10.3390/cancers13102432. Cancers (Basel). 2021. PMID: 34069810 Free PMC article.
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