Lessen LN - Search Results

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Mechanisms that ensure speed and fidelity in eukaryotic translation termination.

Lawson MR, Lessen LN, Wang J, Prabhakar A, Corsepius NC, Green R, Puglisi JD. Lawson MR, et al. Among authors: lessen ln. Science. 2021 Aug 20;373(6557):876-882. doi: 10.1126/science.abi7801. Science. 2021. PMID: 34413231 Free PMC article.

Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.

Tesina P, Lessen LN, Buschauer R, Cheng J, Wu CC, Berninghausen O, Buskirk AR, Becker T, Beckmann R, Green R. Tesina P, et al. Among authors: lessen ln. EMBO J. 2020 Feb 3;39(3):e103365. doi: 10.15252/embj.2019103365. Epub 2019 Dec 20. EMBO J. 2020. PMID: 31858614 Free PMC article.

Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation.

Veltri AJ, D'Orazio KN, Lessen LN, Loll-Krippleber R, Brown GW, Green R. Veltri AJ, et al. Among authors: lessen ln. Elife. 2022 Jul 27;11:e76038. doi: 10.7554/eLife.76038. Elife. 2022. PMID: 35894211 Free PMC article.

Genetic screens in Saccharomyces cerevisiae identify a role for 40S ribosome recycling factors Tma20 and Tma22 in nonsense-mediated decay.

Pacheco M, D'Orazio KN, Lessen LN, Veltri AJ, Neiman Z, Loll-Krippleber R, Brown GW, Green R. Pacheco M, et al. Among authors: lessen ln. G3 (Bethesda). 2024 Mar 6;14(3):jkad295. doi: 10.1093/g3journal/jkad295. G3 (Bethesda). 2024. PMID: 38198768 Free PMC article.

Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.

Williams JA, Biancucci M, Lessen L, Tian S, Balsaraf A, Chen L, Chesterman C, Maruggi G, Vandepaer S, Huang Y, Mallett CP, Steff AM, Bottomley MJ, Malito E, Wahome N, Harshbarger WD. Williams JA, et al. Sci Adv. 2023 Jun 9;9(23):eadg0330. doi: 10.1126/sciadv.adg0330. Epub 2023 Jun 7. Sci Adv. 2023. PMID: 37285422 Free PMC article.

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