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Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells.
Okajima D, Yasuda S, Maejima T, Karibe T, Sakurai K, Aida T, Toki T, Yamaguchi J, Kitamura M, Kamei R, Fujitani T, Honda T, Shibutani T, Muramatsu S, Nakada T, Goto R, Takahashi S, Yamaguchi M, Hamada H, Noguchi Y, Murakami M, Abe Y, Agatsuma T. Okajima D, et al. Among authors: maejima t. Mol Cancer Ther. 2021 Dec;20(12):2329-2340. doi: 10.1158/1535-7163.MCT-21-0206. Epub 2021 Aug 19. Mol Cancer Ther. 2021. PMID: 34413126 Free PMC article.
DS-7300a, a DNA Topoisomerase I Inhibitor, DXd-Based Antibody-Drug Conjugate Targeting B7-H3, Exerts Potent Antitumor Activities in Preclinical Models.
Yamato M, Hasegawa J, Maejima T, Hattori C, Kumagai K, Watanabe A, Nishiya Y, Shibutani T, Aida T, Hayakawa I, Nakada T, Abe Y, Agatsuma T. Yamato M, et al. Among authors: maejima t. Mol Cancer Ther. 2022 Apr 1;21(4):635-646. doi: 10.1158/1535-7163.MCT-21-0554. Mol Cancer Ther. 2022. PMID: 35149548 Free PMC article.
Antitumor Activity and Biomarker Analysis for TROP2 Antibody-Drug Conjugate Datopotamab Deruxtecan in Patient-Derived Breast Cancer Xenograft Models.
Meric-Bernstam F, Yuca E, Evans KW, Zhao M, Maejima T, Karibe T, Raso MG, Tang X, Zheng X, Rizvi YQ, Akcakanat A, Scott SM, Wang B, Byers LA, Tripathy D, Okajima D, Damodaran S. Meric-Bernstam F, et al. Among authors: maejima t. Clin Cancer Res. 2025 Feb 3;31(3):573-587. doi: 10.1158/1078-0432.CCR-24-1948. Clin Cancer Res. 2025. PMID: 39585341 Free PMC article.
Mixed Type of Malignant Mesothelioma in an Aged Male ICR Mouse.
Shirai M, Maejima T, Tanimoto T, Kumagai K, Makino T, Kai K, Teranishi M, Sanbuissho A. Shirai M, et al. Among authors: maejima t. J Toxicol Pathol. 2011 Sep;24(3):169-72. doi: 10.1293/tox.24.169. Epub 2011 Oct 12. J Toxicol Pathol. 2011. PMID: 22272057 Free PMC article.
140 results