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Genetic and environmental exposures constrain epigenetic drift over the human life course.
Shah S, McRae AF, Marioni RE, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Starr JM, Wray NR, Deary IJ, Visscher PM. Shah S, et al. Among authors: cox sr. Genome Res. 2014 Nov;24(11):1725-33. doi: 10.1101/gr.176933.114. Epub 2014 Sep 23. Genome Res. 2014. PMID: 25249537 Free PMC article.
The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.
Marioni RE, Shah S, McRae AF, Ritchie SJ, Muniz-Terrera G, Harris SE, Gibson J, Redmond P, Cox SR, Pattie A, Corley J, Taylor A, Murphy L, Starr JM, Horvath S, Visscher PM, Wray NR, Deary IJ. Marioni RE, et al. Among authors: cox sr. Int J Epidemiol. 2015 Aug;44(4):1388-96. doi: 10.1093/ije/dyu277. Epub 2015 Jan 22. Int J Epidemiol. 2015. PMID: 25617346 Free PMC article.
DNA methylation age of blood predicts all-cause mortality in later life.
Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. Marioni RE, et al. Among authors: cox sr. Genome Biol. 2015 Jan 30;16(1):25. doi: 10.1186/s13059-015-0584-6. Genome Biol. 2015. PMID: 25633388 Free PMC article.
Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151).
Davies G, Marioni RE, Liewald DC, Hill WD, Hagenaars SP, Harris SE, Ritchie SJ, Luciano M, Fawns-Ritchie C, Lyall D, Cullen B, Cox SR, Hayward C, Porteous DJ, Evans J, McIntosh AM, Gallacher J, Craddock N, Pell JP, Smith DJ, Gale CR, Deary IJ. Davies G, et al. Among authors: cox sr. Mol Psychiatry. 2016 Jun;21(6):758-67. doi: 10.1038/mp.2016.45. Epub 2016 Apr 5. Mol Psychiatry. 2016. PMID: 27046643 Free PMC article.
Brain age predicts mortality.
Cole JH, Ritchie SJ, Bastin ME, Valdés Hernández MC, Muñoz Maniega S, Royle N, Corley J, Pattie A, Harris SE, Zhang Q, Wray NR, Redmond P, Marioni RE, Starr JM, Cox SR, Wardlaw JM, Sharp DJ, Deary IJ. Cole JH, et al. Among authors: cox sr. Mol Psychiatry. 2018 May;23(5):1385-1392. doi: 10.1038/mp.2017.62. Epub 2017 Apr 25. Mol Psychiatry. 2018. PMID: 28439103 Free PMC article.
Genetic contributions to Trail Making Test performance in UK Biobank.
Hagenaars SP, Cox SR, Hill WD, Davies G, Liewald DCM; CHARGE consortium Cognitive Working Group; Harris SE, McIntosh AM, Gale CR, Deary IJ. Hagenaars SP, et al. Among authors: cox sr. Mol Psychiatry. 2018 Jul;23(7):1575-1583. doi: 10.1038/mp.2017.189. Epub 2017 Sep 19. Mol Psychiatry. 2018. PMID: 28924184
296 results