Hope KJ - Search Results

1

Arhgef2 regulates mitotic spindle orientation in hematopoietic stem cells and is essential for productive hematopoiesis.

Chan DCH, Xu J, Vujovic A, Wong N, Gordon V, de Rooij LPMH, Moreira S, Joyce CE, La Rose J, Sandí MJ, Doble BW, Novina CD, Rottapel RK, Hope KJ. Chan DCH, et al. Among authors: hope kj. Blood Adv. 2021 Aug 24;5(16):3120-3133. doi: 10.1182/bloodadvances.2020002539. Blood Adv. 2021. PMID: 34406376 Free PMC article.

2

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2.

Ting SB, Deneault E, Hope K, Cellot S, Chagraoui J, Mayotte N, Dorn JF, Laverdure JP, Harvey M, Hawkins ED, Russell SM, Maddox PS, Iscove NN, Sauvageau G. Ting SB, et al. Blood. 2012 Mar 15;119(11):2510-22. doi: 10.1182/blood-2011-11-393272. Epub 2011 Dec 14. Blood. 2012. PMID: 22174158 Free article.

3

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity.

Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G. Cellot S, et al. Among authors: hope kj. Blood. 2013 Aug 29;122(9):1545-55. doi: 10.1182/blood-2013-04-496281. Epub 2013 Jun 18. Blood. 2013. PMID: 23777767 Free PMC article.

4

Post-transcriptional regulation in hematopoiesis: RNA binding proteins take control ¹.

de Rooij LPMH, Chan DCH, Keyvani Chahi A, Hope KJ. de Rooij LPMH, et al. Among authors: hope kj. Biochem Cell Biol. 2019 Feb;97(1):10-20. doi: 10.1139/bcb-2017-0310. Epub 2018 Jun 13. Biochem Cell Biol. 2019. PMID: 29898370 Review.

5

Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance.

Ly M, Rentas S, Vujovic A, Wong N, Moreira S, Xu J, Holzapfel N, Bhatia S, Tran D, Minden MD, Draper JS, Hope KJ. Ly M, et al. Among authors: hope kj. Cancer Res. 2019 Nov 15;79(22):5799-5811. doi: 10.1158/0008-5472.CAN-19-0274. Epub 2019 Sep 13. Cancer Res. 2019. PMID: 31519687

6

Making a bet on RET for hematopoietic stem cell expansion.

Hope KJ. Hope KJ. Blood. 2020 Nov 26;136(22):2484-2486. doi: 10.1182/blood.2020007667. Blood. 2020. PMID: 33242328 Free article. No abstract available.

7

Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis.

Salim SK, Xu J, Wong N, Venugopal C, Hope KJ, Singh SK. Salim SK, et al. Among authors: hope kj. STAR Protoc. 2020 Oct 7;1(3):100124. doi: 10.1016/j.xpro.2020.100124. eCollection 2020 Dec 18. STAR Protoc. 2020. PMID: 33377018 Free PMC article.

8

PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal.

Keyvani Chahi A, Belew MS, Xu J, Chen HTT, Rentas S, Voisin V, Krivdova G, Lechman E, Marhon SA, De Carvalho DD, Dick JE, Bader GD, Hope KJ. Keyvani Chahi A, et al. Among authors: hope kj. Blood. 2022 Sep 1;140(9):992-1008. doi: 10.1182/blood.2021014698. Blood. 2022. PMID: 35639948 Free PMC article.

9

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

Devoucoux M, Fort V, Khelifi G, Xu J, Alerasool N, Galloy M, Wong N, Bourriquen G, Fradet-Turcotte A, Taipale M, Hope K, Hussein SMI, Côté J. Devoucoux M, et al. Cell Rep. 2022 Jun 14;39(11):110947. doi: 10.1016/j.celrep.2022.110947. Cell Rep. 2022. PMID: 35705031 Free article.

10

The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors.

Liu L, Vujovic A, Deshpande NP, Sathe S, Anande G, Chen HTT, Xu J, Minden MD, Yeo GW, Unnikrishnan A, Hope KJ, Lu Y. Liu L, et al. Among authors: hope kj. Nat Commun. 2022 Jul 4;13(1):3833. doi: 10.1038/s41467-022-31155-0. Nat Commun. 2022. PMID: 35781533 Free PMC article.

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