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Critical Role for Hepatocyte-Specific eNOS in NAFLD and NASH.
Cunningham RP, Moore MP, Dashek RJ, Meers GM, Takahashi T, Sheldon RD, Wheeler AA, Diaz-Arias A, Ibdah JA, Parks EJ, Thyfault JP, Rector RS. Cunningham RP, et al. Among authors: wheeler aa. Diabetes. 2021 Nov;70(11):2476-2491. doi: 10.2337/db20-1228. Epub 2021 Aug 11. Diabetes. 2021. PMID: 34380696 Free PMC article.
Hepatocellular RECK as a Critical Regulator of Metabolic Dysfunction-associated Steatohepatitis Development.
Dashek RJ, Cunningham RP, Taylor CL, Alessi I, Diaz C, Meers GM, Wheeler AA, Ibdah JA, Parks EJ, Yoshida T, Chandrasekar B, Rector RS. Dashek RJ, et al. Among authors: wheeler aa. Cell Mol Gastroenterol Hepatol. 2024;18(3):101365. doi: 10.1016/j.jcmgh.2024.101365. Epub 2024 May 24. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38797477 Free PMC article.
Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise.
Jurrissen TJ, Grunewald ZI, Woodford ML, Winn NC, Ball JR, Smith TN, Wheeler AA, Rawlings AL, Staveley-O'Carroll KF, Ji Y, Fay WP, Paradis P, Schiffrin EL, Vieira-Potter VJ, Fadel PJ, Martinez-Lemus LA, Padilla J. Jurrissen TJ, et al. Among authors: wheeler aa. Am J Physiol Endocrinol Metab. 2019 Sep 1;317(3):E548-E558. doi: 10.1152/ajpendo.00178.2019. Epub 2019 Jul 16. Am J Physiol Endocrinol Metab. 2019. PMID: 31310581 Free PMC article.
ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance.
Ghiarone T, Castorena-Gonzalez JA, Foote CA, Ramirez-Perez FI, Ferreira-Santos L, Cabral-Amador FJ, de la Torre R, Ganga RR, Wheeler AA, Manrique-Acevedo C, Padilla J, Martinez-Lemus LA. Ghiarone T, et al. Among authors: wheeler aa. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H688-H701. doi: 10.1152/ajpheart.00039.2022. Epub 2022 Aug 26. Am J Physiol Heart Circ Physiol. 2022. PMID: 36018759 Free PMC article.
32 results