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An Engineered IL15 Cytokine Mutein Fused to an Anti-PD1 Improves Intratumoral T-cell Function and Antitumor Immunity.
Xu Y, Carrascosa LC, Yeung YA, Chu ML, Yang W, Djuretic I, Pappas DC, Zeytounian J, Ge Z, de Ruiter V, Starbeck-Miller GR, Patterson J, Rigas D, Chen SH, Kraynov E, Boor PP, Noordam L, Doukas M, Tsao D, Ijzermans JN, Guo J, Grünhagen DJ, Erdmann J, Verheij J, van Royen ME, Doornebosch PG, Feldman R, Park T, Mahmoudi S, Dorywalska M, Ni I, Chin SM, Mistry T, Mosyak L, Lin L, Ching KA, Lindquist KC, Ji C, Londono LM, Kuang B, Rickert R, Kwekkeboom J, Sprengers D, Huang TH, Chaparro-Riggers J. Xu Y, et al. Among authors: chu ml. Cancer Immunol Res. 2021 Oct;9(10):1141-1157. doi: 10.1158/2326-6066.CIR-21-0058. Epub 2021 Aug 10. Cancer Immunol Res. 2021. PMID: 34376502
The respiratory microbiome is linked to the severity of RSV infections and the persistence of symptoms in children.
Kristensen M, de Steenhuijsen Piters WAA, Wildenbeest J, van Houten MA, Zuurbier RP, Hasrat R, Arp K, Chu MLJN, Billard M, Heikkinen T, Cunningham S, Snape M, Drysdale SB, Thwaites RS, Martinon-Torres F, Pollard AJ, Openshaw PJM, Aerssen J, Binkowska J, Bont L, Bogaert D; REspiratory Syncytial virus Consortium in EUrope (RESCEU) investigators. Kristensen M, et al. Among authors: chu mljn. Cell Rep Med. 2024 Dec 17;5(12):101836. doi: 10.1016/j.xcrm.2024.101836. Epub 2024 Dec 5. Cell Rep Med. 2024. PMID: 39642873 Free article.
Salivary polyreactive antibodies and Haemophilus influenzae are associated with respiratory infection severity in young children with recurrent respiratory infections.
Koenen MH, de Steenhuijsen Piters WAA, de Jonge MI, Langereis JD, Nierkens S, Chu MLJN, van der Woude R, de Vries RP, Sanders EAM, Bogaert D, van der Vries E, Boes M, Verhagen LM. Koenen MH, et al. Among authors: chu mljn. Eur Respir J. 2024 Oct 3;64(4):2400317. doi: 10.1183/13993003.00317-2024. Print 2024 Oct. Eur Respir J. 2024. PMID: 39117429 Free PMC article.
Host and environmental factors shape upper airway microbiota and respiratory health across the human lifespan.
Odendaal ML, de Steenhuijsen Piters WAA, Franz E, Chu MLJN, Groot JA, van Logchem EM, Hasrat R, Kuiling S, Pijnacker R, Mariman R, Trzciński K, van der Klis FRM, Sanders EAM, Smit LAM, Bogaert D, Bosch T. Odendaal ML, et al. Among authors: chu mljn. Cell. 2024 Aug 22;187(17):4571-4585.e15. doi: 10.1016/j.cell.2024.07.008. Epub 2024 Aug 1. Cell. 2024. PMID: 39094567 Free article.
Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infection.
Sintoris S, Binkowska JM, Gillan JL, Zuurbier RP, Twynam-Perkins J, Kristensen M, Melrose L, Parga PL, Rodriguez AR, Chu ML, van Boeckel SR, Wildenbeest JG, Bowdish DME, Currie AJ, Thwaites RS, Schwarze J, van Houten MA, Boardman JP, Cunningham S, Bogaert D, Davidson DJ. Sintoris S, et al. Among authors: chu ml. Sci Rep. 2024 Jun 17;14(1):13928. doi: 10.1038/s41598-024-64446-1. Sci Rep. 2024. PMID: 38886476 Free PMC article.
567 results