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Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights.
Al-Sanea MM, Elkamhawy A, Paik S, Lee K, El Kerdawy AM, Syed Nasir Abbas B, Joo Roh E, Eldehna WM, Elshemy HAH, Bakr RB, Ali Farahat I, Alzarea AI, Alzarea SI, Alharbi KS, Abdelgawad MA. Al-Sanea MM, et al. Bioorg Med Chem. 2020 Jul 1;28(13):115525. doi: 10.1016/j.bmc.2020.115525. Epub 2020 Apr 25. Bioorg Med Chem. 2020. PMID: 32371117
New Cytotoxic Natural Products from the Red Sea Sponge Stylissa carteri.
Abdelhameed RFA, Habib ES, Eltahawy NA, Hassanean HA, Ibrahim AK, Mohammed AF, Fayez S, Hayallah AM, Yamada K, Behery FA, Al-Sanea MM, Alzarea SI, Bringmann G, Ahmed SA, Abdelmohsen UR. Abdelhameed RFA, et al. Mar Drugs. 2020 May 3;18(5):241. doi: 10.3390/md18050241. Mar Drugs. 2020. PMID: 32375235 Free PMC article.
Novel [(N-alkyl-3-indolylmethylene)hydrazono]oxindoles arrest cell cycle and induce cell apoptosis by inhibiting CDK2 and Bcl-2: synthesis, biological evaluation and in silico studies.
Al-Warhi T, Abo-Ashour MF, Almahli H, Alotaibi OJ, Al-Sanea MM, Al-Ansary GH, Ahmed HY, Elaasser MM, Eldehna WM, Abdel-Aziz HA. Al-Warhi T, et al. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1300-1309. doi: 10.1080/14756366.2020.1773814. J Enzyme Inhib Med Chem. 2020. PMID: 32522063 Free PMC article.
3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies.
Alkhaldi AAM, Al-Sanea MM, Nocentini A, Eldehna WM, Elsayed ZM, Bonardi A, Abo-Ashour MF, El-Damasy AK, Abdel-Maksoud MS, Al-Warhi T, Gratteri P, Abdel-Aziz HA, Supuran CT, El-Haggar R. Alkhaldi AAM, et al. Eur J Med Chem. 2020 Dec 1;207:112745. doi: 10.1016/j.ejmech.2020.112745. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32877804
88 results