Neelamegam R - Search Results

1

In vivo imaging of mGlu5 receptor expression in humans with Fragile X Syndrome towards development of a potential biomarker.

Mody M, Petibon Y, Han P, Kuruppu D, Ma C, Yokell D, Neelamegam R, Normandin MD, Fakhri GE, Brownell AL. Mody M, et al. Among authors: neelamegam r. Sci Rep. 2021 Aug 5;11(1):15897. doi: 10.1038/s41598-021-94967-y. Sci Rep. 2021. PMID: 34354107 Free PMC article.

2

A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [¹⁸ F]-THK-5351.

Neelamegam R, Yokell DL, Rice PA, Furumoto S, Kudo Y, Okamura N, El Fakhri G. Neelamegam R, et al. J Labelled Comp Radiopharm. 2017 Feb;60(2):140-146. doi: 10.1002/jlcr.3482. Epub 2017 Jan 25. J Labelled Comp Radiopharm. 2017. PMID: 27859483

3

cGMP production of the radiopharmaceutical [¹⁸ F]MK-6240 for PET imaging of human neurofibrillary tangles.

Collier TL, Yokell DL, Livni E, Rice PA, Celen S, Serdons K, Neelamegam R, Bormans G, Harris D, Walji A, Hostetler ED, Bennacef I, Vasdev N. Collier TL, et al. Among authors: neelamegam r. J Labelled Comp Radiopharm. 2017 May 15;60(5):263-269. doi: 10.1002/jlcr.3496. Epub 2017 Mar 23. J Labelled Comp Radiopharm. 2017. PMID: 28185305

4

[¹⁸F]Fluorocholine and [¹⁸F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC and LAM.

Verwer EE, Kavanagh TR, Mischler WJ, Feng Y, Takahashi K, Wang S, Shoup TM, Neelamegam R, Yang J, Guehl NJ, Ran C, Massefski W, Cui Y, El-Chemaly S, Sadow PM, Oldham WM, Kijewski MF, El Fakhri G, Normandin MD, Priolo C. Verwer EE, et al. Among authors: neelamegam r. Clin Cancer Res. 2018 Dec 1;24(23):5925-5938. doi: 10.1158/1078-0432.CCR-17-3693. Epub 2018 Jul 27. Clin Cancer Res. 2018. PMID: 30054282 Free PMC article.

5

Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue.

Aguero C, Dhaynaut M, Normandin MD, Amaral AC, Guehl NJ, Neelamegam R, Marquie M, Johnson KA, El Fakhri G, Frosch MP, Gomez-Isla T. Aguero C, et al. Among authors: neelamegam r. Acta Neuropathol Commun. 2019 Mar 11;7(1):37. doi: 10.1186/s40478-019-0686-6. Acta Neuropathol Commun. 2019. PMID: 30857558 Free PMC article.

6

Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET).

Lan Y, Bai P, Chen Z, Neelamegam R, Placzek MS, Wang H, Fiedler SA, Yang J, Yuan G, Qu X, Schmidt HR, Song J, Normandin MD, Ran C, Wang C. Lan Y, et al. Among authors: neelamegam r. Acta Pharm Sin B. 2019 Nov;9(6):1204-1215. doi: 10.1016/j.apsb.2019.07.002. Epub 2019 Jul 11. Acta Pharm Sin B. 2019. PMID: 31867166 Free PMC article.

7

Development, validation and regulatory acceptance of improved purification and simplified quality control of [¹³N] Ammonia.

Yokell DL, Rice PA, Neelamegam R, El Fakhri G. Yokell DL, et al. Among authors: neelamegam r. EJNMMI Radiopharm Chem. 2020 May 13;5(1):11. doi: 10.1186/s41181-020-00097-7. EJNMMI Radiopharm Chem. 2020. PMID: 32405797 Free PMC article.

8

Design, Synthesis, and Characterization of Benzimidazole Derivatives as Positron Emission Tomography Imaging Ligands for Metabotropic Glutamate Receptor 2.

Yuan G, Qu X, Zheng B, Neelamegam R, Afshar S, Iyengar S, Pan C, Wang J, Kang HJ, Ondrechen MJ, Poutiainen P, El Fakhri G, Zhang Z, Brownell AL. Yuan G, et al. Among authors: neelamegam r. J Med Chem. 2020 Oct 22;63(20):12060-12072. doi: 10.1021/acs.jmedchem.0c01394. Epub 2020 Oct 7. J Med Chem. 2020. PMID: 32981322 Free PMC article.

9

Evaluation of the potassium channel tracer [¹⁸F]3F4AP in rhesus macaques.

Guehl NJ, Ramos-Torres KM, Linnman C, Moon SH, Dhaynaut M, Wilks MQ, Han PK, Ma C, Neelamegam R, Zhou YP, Popko B, Correia JA, Reich DS, Fakhri GE, Herscovitch P, Normandin MD, Brugarolas P. Guehl NJ, et al. Among authors: neelamegam r. J Cereb Blood Flow Metab. 2021 Jul;41(7):1721-1733. doi: 10.1177/0271678X20963404. Epub 2020 Oct 22. J Cereb Blood Flow Metab. 2021. PMID: 33090071 Free PMC article.

10

Radiochemical Synthesis and Evaluation in Non-Human Primates of 3-[¹¹C]methoxy-4-aminopyridine: A Novel PET Tracer for Imaging Potassium Channels in the CNS.

Guehl NJ, Neelamegam R, Zhou YP, Moon SH, Dhaynaut M, El Fakhri G, Normandin MD, Brugarolas P. Guehl NJ, et al. Among authors: neelamegam r. ACS Chem Neurosci. 2021 Feb 17;12(4):756-765. doi: 10.1021/acschemneuro.0c00791. Epub 2021 Feb 4. ACS Chem Neurosci. 2021. PMID: 33539063 Free PMC article.

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