He X - Search Results

1

Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design.

Lu S, He X, Yang Z, Chai Z, Zhou S, Wang J, Rehman AU, Ni D, Pu J, Sun J, Zhang J. Lu S, et al. Among authors: he x. Nat Commun. 2021 Aug 5;12(1):4721. doi: 10.1038/s41467-021-25020-9. Nat Commun. 2021. PMID: 34354057 Free PMC article.

2

Molecular dynamics simulations provide insights into the origin of gleevec's selectivity toward human tyrosine kinases.

Wang L, Zheng G, Liu X, Ni D, He X, Cheng J, Lu S. Wang L, et al. Among authors: he x. J Biomol Struct Dyn. 2019 Jul;37(10):2733-2744. doi: 10.1080/07391102.2018.1496139. Epub 2018 Nov 1. J Biomol Struct Dyn. 2019. PMID: 30052122

3

How does the novel T315L mutation of breakpoint cluster region-abelson (BCR-ABL) kinase confer resistance to ponatinib: a comparative molecular dynamics simulation study.

Zhang H, He X, Ni D, Mou L, Chen X, Lu S. Zhang H, et al. Among authors: he x. J Biomol Struct Dyn. 2020 Jan;38(1):89-100. doi: 10.1080/07391102.2019.1567390. Epub 2019 Feb 5. J Biomol Struct Dyn. 2020. PMID: 30661457

4

Allosteric Modulator Discovery: From Serendipity to Structure-Based Design.

Lu S, He X, Ni D, Zhang J. Lu S, et al. Among authors: he x. J Med Chem. 2019 Jul 25;62(14):6405-6421. doi: 10.1021/acs.jmedchem.8b01749. Epub 2019 Mar 7. J Med Chem. 2019. PMID: 30817889

5

Drugging K-Ras^G12C through covalent inhibitors: Mission possible?

Ni D, Li X, He X, Zhang H, Zhang J, Lu S. Ni D, et al. Among authors: he x. Pharmacol Ther. 2019 Oct;202:1-17. doi: 10.1016/j.pharmthera.2019.06.007. Epub 2019 Jun 22. Pharmacol Ther. 2019. PMID: 31233765 Review.

6

Emergence of allosteric drug-resistance mutations: new challenges for allosteric drug discovery.

Lu S, Qiu Y, Ni D, He X, Pu J, Zhang J. Lu S, et al. Among authors: he x. Drug Discov Today. 2020 Jan;25(1):177-184. doi: 10.1016/j.drudis.2019.10.006. Epub 2019 Oct 18. Drug Discov Today. 2020. PMID: 31634592 Review.

7

Unraveling allosteric landscapes of allosterome with ASD.

Liu X, Lu S, Song K, Shen Q, Ni D, Li Q, He X, Zhang H, Wang Q, Chen Y, Li X, Wu J, Sheng C, Chen G, Liu Y, Lu X, Zhang J. Liu X, et al. Among authors: he x. Nucleic Acids Res. 2020 Jan 8;48(D1):D394-D401. doi: 10.1093/nar/gkz958. Nucleic Acids Res. 2020. PMID: 31665428 Free PMC article.

8

Characteristics of Allosteric Proteins, Sites, and Modulators.

He X, Ni D, Lu S, Zhang J. He X, et al. Adv Exp Med Biol. 2019;1163:107-139. doi: 10.1007/978-981-13-8719-7_6. Adv Exp Med Biol. 2019. PMID: 31707702 Review.

9

Insight into the mechanism of allosteric activation of PI3Kα by oncoprotein K-Ras4B.

Li X, Dai J, Ni D, He X, Zhang H, Zhang J, Fu Q, Liu Y, Lu S. Li X, et al. Among authors: he x. Int J Biol Macromol. 2020 Feb 1;144:643-655. doi: 10.1016/j.ijbiomac.2019.12.020. Epub 2019 Dec 6. Int J Biol Macromol. 2020. PMID: 31816384

10

Zinc-mediated conformational preselection mechanism in the allosteric control of DNA binding to the zinc transcriptional regulator (ZitR).

He X, Ni D, Zhang H, Li X, Zhang J, Fu Q, Liu Y, Lu S. He X, et al. Sci Rep. 2020 Aug 6;10(1):13276. doi: 10.1038/s41598-020-70381-8. Sci Rep. 2020. PMID: 32764589 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

29,058 results

Search Page

Filters