Burke JE - Search Results

1

HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases.

Rathinaswamy MK, Fleming KD, Dalwadi U, Pardon E, Harris NJ, Yip CK, Steyaert J, Burke JE. Rathinaswamy MK, et al. Among authors: burke je. Structure. 2021 Dec 2;29(12):1371-1381.e6. doi: 10.1016/j.str.2021.07.002. Epub 2021 Aug 3. Structure. 2021. PMID: 34348129 Free article.

2

Synergy in activating class I PI3Ks.

Burke JE, Williams RL. Burke JE, et al. Trends Biochem Sci. 2015 Feb;40(2):88-100. doi: 10.1016/j.tibs.2014.12.003. Epub 2015 Jan 5. Trends Biochem Sci. 2015. PMID: 25573003 Review.

3

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.

Rostislavleva K, Soler N, Ohashi Y, Zhang L, Pardon E, Burke JE, Masson GR, Johnson C, Steyaert J, Ktistakis NT, Williams RL. Rostislavleva K, et al. Among authors: burke je. Science. 2015 Oct 9;350(6257):aac7365. doi: 10.1126/science.aac7365. Science. 2015. PMID: 26450213 Free PMC article.

4

Probing the dynamic regulation of peripheral membrane proteins using hydrogen deuterium exchange-MS (HDX-MS).

Vadas O, Burke JE. Vadas O, et al. Among authors: burke je. Biochem Soc Trans. 2015 Oct;43(5):773-86. doi: 10.1042/BST20150065. Biochem Soc Trans. 2015. PMID: 26517882 Review.

5

Type III phosphatidylinositol 4 kinases: structure, function, regulation, signalling and involvement in disease.

Dornan GL, McPhail JA, Burke JE. Dornan GL, et al. Among authors: burke je. Biochem Soc Trans. 2016 Feb;44(1):260-6. doi: 10.1042/BST20150219. Biochem Soc Trans. 2016. PMID: 26862213 Review.

6

The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3.

McPhail JA, Ottosen EH, Jenkins ML, Burke JE. McPhail JA, et al. Among authors: burke je. Structure. 2017 Jan 3;25(1):121-131. doi: 10.1016/j.str.2016.11.016. Epub 2016 Dec 15. Structure. 2017. PMID: 27989622 Free article.

7

Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1.

Dornan GL, Siempelkamp BD, Jenkins ML, Vadas O, Lucas CL, Burke JE. Dornan GL, et al. Among authors: burke je. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1982-1987. doi: 10.1073/pnas.1617244114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167755 Free PMC article.

8

Molecular mechanism of activation of class IA phosphoinositide 3-kinases (PI3Ks) by membrane-localized HRas.

Siempelkamp BD, Rathinaswamy MK, Jenkins ML, Burke JE. Siempelkamp BD, et al. Among authors: burke je. J Biol Chem. 2017 Jul 21;292(29):12256-12266. doi: 10.1074/jbc.M117.789263. Epub 2017 May 17. J Biol Chem. 2017. PMID: 28515318 Free PMC article.

9

Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.

Gentile DR, Rathinaswamy MK, Jenkins ML, Moss SM, Siempelkamp BD, Renslo AR, Burke JE, Shokat KM. Gentile DR, et al. Among authors: burke je. Cell Chem Biol. 2017 Dec 21;24(12):1455-1466.e14. doi: 10.1016/j.chembiol.2017.08.025. Epub 2017 Oct 12. Cell Chem Biol. 2017. PMID: 29033317 Free PMC article.

10

Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases.

Dornan GL, Burke JE. Dornan GL, et al. Among authors: burke je. Front Immunol. 2018 Mar 19;9:575. doi: 10.3389/fimmu.2018.00575. eCollection 2018. Front Immunol. 2018. PMID: 29616047 Free PMC article. Review.

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