Kortholt A - Search Results

1

Forty-five years of cGMP research in Dictyostelium: understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis.

van Haastert PJM, Keizer-Gunnink I, Pots H, Ortiz-Mateos C, Veltman D, van Egmond W, Kortholt A. van Haastert PJM, et al. Among authors: kortholt a. Mol Biol Cell. 2021 Oct 1;32(20):ar8. doi: 10.1091/mbc.E21-04-0171. Epub 2021 Aug 4. Mol Biol Cell. 2021. PMID: 34347507 Free PMC article. Review.

2

Phosducin-like proteins in Dictyostelium discoideum: implications for the phosducin family of proteins.

Blaauw M, Knol JC, Kortholt A, Roelofs J, Ruchira, Postma M, Visser AJ, van Haastert PJ. Blaauw M, et al. Among authors: kortholt a. EMBO J. 2003 Oct 1;22(19):5047-57. doi: 10.1093/emboj/cdg508. EMBO J. 2003. PMID: 14517243 Free PMC article.

3

DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of dictyostelium cells.

Bader S, Kortholt A, Snippe H, Van Haastert PJ. Bader S, et al. Among authors: kortholt a. J Biol Chem. 2006 Jul 21;281(29):20018-26. doi: 10.1074/jbc.M600040200. Epub 2006 Apr 27. J Biol Chem. 2006. PMID: 16644729 Free article.

4

Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum.

Kortholt A, Rehmann H, Kae H, Bosgraaf L, Keizer-Gunnink I, Weeks G, Wittinghofer A, Van Haastert PJ. Kortholt A, et al. J Biol Chem. 2006 Aug 18;281(33):23367-76. doi: 10.1074/jbc.M600804200. Epub 2006 Jun 12. J Biol Chem. 2006. PMID: 16769729 Free article.

5

Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.

Bader S, Kortholt A, Van Haastert PJ. Bader S, et al. Among authors: kortholt a. Biochem J. 2007 Feb 15;402(1):153-61. doi: 10.1042/BJ20061153. Biochem J. 2007. PMID: 17040207 Free PMC article.

6

Regulation of phagocytosis in Dictyostelium by the inositol 5-phosphatase OCRL homolog Dd5P4.

Loovers HM, Kortholt A, de Groote H, Whitty L, Nussbaum RL, van Haastert PJ. Loovers HM, et al. Among authors: kortholt a. Traffic. 2007 May;8(5):618-28. doi: 10.1111/j.1600-0854.2007.00546.x. Epub 2007 Mar 2. Traffic. 2007. PMID: 17343681 Free article.

7

Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs.

Kae H, Kortholt A, Rehmann H, Insall RH, Van Haastert PJ, Spiegelman GB, Weeks G. Kae H, et al. Among authors: kortholt a. EMBO Rep. 2007 May;8(5):477-82. doi: 10.1038/sj.embor.7400936. Epub 2007 Mar 23. EMBO Rep. 2007. PMID: 17380187 Free PMC article.

8

Chemoattractants and chemorepellents act by inducing opposite polarity in phospholipase C and PI3-kinase signaling.

Keizer-Gunnink I, Kortholt A, Van Haastert PJ. Keizer-Gunnink I, et al. Among authors: kortholt a. J Cell Biol. 2007 May 21;177(4):579-85. doi: 10.1083/jcb.200611046. J Cell Biol. 2007. PMID: 17517960 Free PMC article.

9

Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis.

van Haastert PJ, Keizer-Gunnink I, Kortholt A. van Haastert PJ, et al. Among authors: kortholt a. J Cell Biol. 2007 Jun 4;177(5):809-16. doi: 10.1083/jcb.200701134. Epub 2007 May 29. J Cell Biol. 2007. PMID: 17535967 Free PMC article.

10

Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis.

Kortholt A, King JS, Keizer-Gunnink I, Harwood AJ, Van Haastert PJ. Kortholt A, et al. Mol Biol Cell. 2007 Dec;18(12):4772-9. doi: 10.1091/mbc.e07-05-0407. Epub 2007 Sep 26. Mol Biol Cell. 2007. PMID: 17898079 Free PMC article.

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