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Design, synthesis and analysis of novel sphingosine kinase-1 inhibitors to improve oral bioavailability.
Butler KJ, Castro AA, Dwyer TS, Hardwick LM, Iacino MC, Manore SG, Mays KM, McGlade CA, Hair LN, Parker EW, Smith MR, Turnow MT, Wilson MR, Woodson SR, Cotham WE, Walla MD, Hurlbert JC, Christian Grattan T. Butler KJ, et al. Among authors: mcglade ca. Bioorg Med Chem Lett. 2021 Oct 15;50:128329. doi: 10.1016/j.bmcl.2021.128329. Epub 2021 Aug 19. Bioorg Med Chem Lett. 2021. PMID: 34418572 Free PMC article.
Engineering P450 TamI as an Iterative Biocatalyst for Selective Late-Stage C-H Functionalization and Epoxidation of Tirandamycin Antibiotics.
Espinoza RV, Haatveit KC, Grossman SW, Tan JY, McGlade CA, Khatri Y, Newmister SA, Schmidt JJ, Garcia-Borràs M, Montgomery J, Houk KN, Sherman DH. Espinoza RV, et al. Among authors: mcglade ca. ACS Catal. 2021 Jul 2;11(13):8304-8316. doi: 10.1021/acscatal.1c01460. Epub 2021 Jun 22. ACS Catal. 2021. PMID: 35003829 Free PMC article.
Photothrombolytics: A light-driven technology for the targeted lysis of thrombi.
Acharya B, McGlade CA, Yin H, Kawano T, Haar L, Mackman N, Sellers RS, Tan X, Bhatt AP, Lawrence DS, Vickerman BM. Acharya B, et al. Among authors: mcglade ca. J Control Release. 2024 Dec 17;378:281-293. doi: 10.1016/j.jconrel.2024.11.059. Online ahead of print. J Control Release. 2024. PMID: 39615753