Lee KY - Search Results

1

Infantile spasms-linked Nedd4-2 mediates hippocampal plasticity and learning via cofilin signaling.

Lee KY, Zhu J, Cutia CA, Christian-Hinman CA, Rhodes JS, Tsai NP. Lee KY, et al. EMBO Rep. 2021 Oct 5;22(10):e52645. doi: 10.15252/embr.202152645. Epub 2021 Aug 3. EMBO Rep. 2021. PMID: 34342389 Free PMC article.

2

Feedback modulation of neural network synchrony and seizure susceptibility by Mdm2-p53-Nedd4-2 signaling.

Jewett KA, Christian CA, Bacos JT, Lee KY, Zhu J, Tsai NP. Jewett KA, et al. Among authors: lee ky. Mol Brain. 2016 Mar 22;9:32. doi: 10.1186/s13041-016-0214-6. Mol Brain. 2016. PMID: 27000207 Free PMC article.

3

Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.

Zhu J, Lee KY, Jewett KA, Man HY, Chung HJ, Tsai NP. Zhu J, et al. Among authors: lee ky. PLoS Genet. 2017 Feb 17;13(2):e1006634. doi: 10.1371/journal.pgen.1006634. eCollection 2017 Feb. PLoS Genet. 2017. PMID: 28212375 Free PMC article.

4

Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity.

Liu DC, Seimetz J, Lee KY, Kalsotra A, Chung HJ, Lu H, Tsai NP. Liu DC, et al. Among authors: lee ky. Hum Mol Genet. 2017 Oct 15;26(20):3895-3908. doi: 10.1093/hmg/ddx276. Hum Mol Genet. 2017. PMID: 29016848 Free PMC article.

5

Loss of fragile X protein FMRP impairs homeostatic synaptic downscaling through tumor suppressor p53 and ubiquitin E3 ligase Nedd4-2.

Lee KY, Jewett KA, Chung HJ, Tsai NP. Lee KY, et al. Hum Mol Genet. 2018 Aug 15;27(16):2805-2816. doi: 10.1093/hmg/ddy189. Hum Mol Genet. 2018. PMID: 29771335 Free PMC article.

6

Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice.

Jewett KA, Lee KY, Eagleman DE, Soriano S, Tsai NP. Jewett KA, et al. Among authors: lee ky. Neuropharmacology. 2018 Aug;138:182-192. doi: 10.1016/j.neuropharm.2018.06.011. Epub 2018 Jun 8. Neuropharmacology. 2018. PMID: 29890190 Free PMC article.

7

Reduced axonal surface expression and phosphoinositide sensitivity in K_v7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy.

Kim EC, Zhang J, Pang W, Wang S, Lee KY, Cavaretta JP, Walters J, Procko E, Tsai NP, Chung HJ. Kim EC, et al. Among authors: lee ky. Neurobiol Dis. 2018 Oct;118:76-93. doi: 10.1016/j.nbd.2018.07.004. Epub 2018 Jul 6. Neurobiol Dis. 2018. PMID: 30008368 Free PMC article.

8

C2-lacking isoform of Nedd4-2 regulates excitatory synaptic strength through GluA1 ubiquitination-independent mechanisms.

Zhu J, Lee KY, Jong TT, Tsai NP. Zhu J, et al. Among authors: lee ky. J Neurochem. 2019 Nov;151(3):289-300. doi: 10.1111/jnc.14840. Epub 2019 Aug 25. J Neurochem. 2019. PMID: 31357244 Free PMC article.

9

ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model.

Liu DC, Lee KY, Lizarazo S, Cook JK, Tsai NP. Liu DC, et al. Among authors: lee ky. Neurobiol Dis. 2021 Oct;158:105450. doi: 10.1016/j.nbd.2021.105450. Epub 2021 Jul 23. Neurobiol Dis. 2021. PMID: 34303799 Free PMC article.

10

Tumor suppressor p53 modulates activity-dependent synapse strengthening, autism-like behavior and hippocampus-dependent learning.

Lee KY, Wang H, Yook Y, Rhodes JS, Christian-Hinman CA, Tsai NP. Lee KY, et al. Mol Psychiatry. 2023 Sep;28(9):3782-3794. doi: 10.1038/s41380-023-02268-9. Epub 2023 Sep 28. Mol Psychiatry. 2023. PMID: 37759036 Free PMC article.

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