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Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer.
Rosigkeit S, Kruchem M, Thies D, Kreft A, Eichler E, Boegel S, Jansky S, Siegl D, Kaps L, Pickert G, Haehnel P, Kindler T, Hartwig UF, Guerra C, Barbacid M, Schuppan D, Bockamp E. Rosigkeit S, et al. Among authors: boegel s. Int J Cancer. 2021 Nov 1;149(9):1670-1682. doi: 10.1002/ijc.33756. Epub 2021 Aug 10. Int J Cancer. 2021. PMID: 34331774
Exploiting the mutanome for tumor vaccination.
Castle JC, Kreiter S, Diekmann J, Löwer M, van de Roemer N, de Graaf J, Selmi A, Diken M, Boegel S, Paret C, Koslowski M, Kuhn AN, Britten CM, Huber C, Türeci O, Sahin U. Castle JC, et al. Among authors: boegel s. Cancer Res. 2012 Mar 1;72(5):1081-91. doi: 10.1158/0008-5472.CAN-11-3722. Epub 2012 Jan 11. Cancer Res. 2012. PMID: 22237626 Free article.
Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells.
Foerster F, Boegel S, Heck R, Pickert G, Rüssel N, Rosigkeit S, Bros M, Strobl S, Kaps L, Aslam M, Diken M, Castle J, Sahin U, Tuettenberg A, Bockamp E, Schuppan D. Foerster F, et al. Among authors: boegel s. Oncoimmunology. 2017 Dec 26;7(4):e1409929. doi: 10.1080/2162402X.2017.1409929. eCollection 2018. Oncoimmunology. 2017. PMID: 29632723 Free PMC article.
Mutanome directed cancer immunotherapy.
Vormehr M, Diken M, Boegel S, Kreiter S, Türeci Ö, Sahin U. Vormehr M, et al. Among authors: boegel s. Curr Opin Immunol. 2016 Apr;39:14-22. doi: 10.1016/j.coi.2015.12.001. Epub 2015 Dec 21. Curr Opin Immunol. 2016. PMID: 26716729 Review.
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
Castle JC, Loewer M, Boegel S, de Graaf J, Bender C, Tadmor AD, Boisguerin V, Bukur T, Sorn P, Paret C, Diken M, Kreiter S, Türeci Ö, Sahin U. Castle JC, et al. Among authors: boegel s. BMC Genomics. 2014 Mar 13;15(1):190. doi: 10.1186/1471-2164-15-190. BMC Genomics. 2014. PMID: 24621249 Free PMC article.
Mutated tumor alleles are expressed according to their DNA frequency.
Castle JC, Loewer M, Boegel S, Tadmor AD, Boisguerin V, de Graaf J, Paret C, Diken M, Kreiter S, Türeci Ö, Sahin U. Castle JC, et al. Among authors: boegel s. Sci Rep. 2014 Apr 22;4:4743. doi: 10.1038/srep04743. Sci Rep. 2014. PMID: 24752137 Free PMC article.
Mutant MHC class II epitopes drive therapeutic immune responses to cancer.
Kreiter S, Vormehr M, van de Roemer N, Diken M, Löwer M, Diekmann J, Boegel S, Schrörs B, Vascotto F, Castle JC, Tadmor AD, Schoenberger SP, Huber C, Türeci Ö, Sahin U. Kreiter S, et al. Among authors: boegel s. Nature. 2015 Apr 30;520(7549):692-6. doi: 10.1038/nature14426. Epub 2015 Apr 22. Nature. 2015. PMID: 25901682 Free PMC article.
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