Koche RP - Search Results

1

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.

Wolfe AL, Zhou Q, Toska E, Galeas J, Ku AA, Koche RP, Bandyopadhyay S, Scaltriti M, Lebrilla CB, McCormick F, Kim SE. Wolfe AL, et al. Among authors: koche rp. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2103592118. doi: 10.1073/pnas.2103592118. Proc Natl Acad Sci U S A. 2021. PMID: 34330832 Free PMC article.

2

Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells.

Chamorro González R, Conrad T, Stöber MC, Xu R, Giurgiu M, Rodriguez-Fos E, Kasack K, Brückner L, van Leen E, Helmsauer K, Dorado Garcia H, Stefanova ME, Hung KL, Bei Y, Schmelz K, Lodrini M, Mundlos S, Chang HY, Deubzer HE, Sauer S, Eggert A, Schulte JH, Schwarz RF, Haase K, Koche RP, Henssen AG. Chamorro González R, et al. Among authors: koche rp. Nat Genet. 2023 May;55(5):880-890. doi: 10.1038/s41588-023-01386-y. Epub 2023 May 4. Nat Genet. 2023. PMID: 37142849 Free PMC article.

3

Metastatic site influences driver gene function in pancreatic cancer.

Tsanov KM, Barriga FM, Ho YJ, Alonso-Curbelo D, Livshits G, Koche RP, Baslan T, Simon J, Tian S, Wuest AN, Luan W, Wilkinson JE, Masilionis I, Dimitrova N, Iacobuzio-Donahue CA, Chaligné R, Pe'er D, Massagué J, Lowe SW. Tsanov KM, et al. Among authors: koche rp. bioRxiv [Preprint]. 2024 Mar 18:2024.03.17.585402. doi: 10.1101/2024.03.17.585402. bioRxiv. 2024. PMID: 38562717 Free PMC article. Preprint.

4

A nucleosome switch primes Hepatitis B Virus infection.

Prescott NA, Mansisidor A, Bram Y, Biaco T, Rendleman J, Faulkner SC, Lemmon AA, Lim C, Hamard PJ, Koche RP, Risca VI, Schwartz RE, David Y. Prescott NA, et al. Among authors: koche rp. bioRxiv [Preprint]. 2024 Jun 12:2023.03.03.531011. doi: 10.1101/2023.03.03.531011. bioRxiv. 2024. PMID: 38915612 Free PMC article. Preprint.

5

Mutational topography reflects clinical neuroblastoma heterogeneity.

Rodriguez-Fos E, Planas-Fèlix M, Burkert M, Puiggròs M, Toedling J, Thiessen N, Blanc E, Szymansky A, Hertwig F, Ishaque N, Beule D, Torrents D, Eggert A, Koche RP, Schwarz RF, Haase K, Schulte JH, Henssen AG. Rodriguez-Fos E, et al. Among authors: koche rp. Cell Genom. 2023 Sep 7;3(10):100402. doi: 10.1016/j.xgen.2023.100402. eCollection 2023 Oct 11. Cell Genom. 2023. PMID: 37868040 Free PMC article.

6

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.

Dunbar AJ, Kim D, Lu M, Farina M, Bowman RL, Yang JL, Park Y, Karzai A, Xiao W, Zaroogian Z, O'Connor K, Mowla S, Gobbo F, Verachi P, Martelli F, Sarli G, Xia L, Elmansy N, Kleppe M, Chen Z, Xiao Y, McGovern E, Snyder J, Krishnan A, Hill C, Cordner K, Zouak A, Salama ME, Yohai J, Tucker E, Chen J, Zhou J, McConnell T, Migliaccio AR, Koche R, Rampal R, Fan R, Levine RL, Hoffman R. Dunbar AJ, et al. Blood. 2023 May 18;141(20):2508-2519. doi: 10.1182/blood.2022015418. Blood. 2023. PMID: 36800567 Free PMC article.

7

PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression.

Toska E, Castel P, Chhangawala S, Arruabarrena-Aristorena A, Chan C, Hristidis VC, Cocco E, Sallaku M, Xu G, Park J, Minuesa G, Shifman SG, Socci ND, Koche R, Leslie CS, Scaltriti M, Baselga J. Toska E, et al. Cell Rep. 2019 Apr 2;27(1):294-306.e5. doi: 10.1016/j.celrep.2019.02.111. Cell Rep. 2019. PMID: 30943409 Free PMC article.

8

2-hydroxyglutarate inhibits MyoD-mediated differentiation by preventing H3K9 demethylation.

Schvartzman JM, Reuter VP, Koche RP, Thompson CB. Schvartzman JM, et al. Among authors: koche rp. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):12851-12856. doi: 10.1073/pnas.1817662116. Epub 2019 Jun 10. Proc Natl Acad Sci U S A. 2019. PMID: 31182575 Free PMC article.

9

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer.

Xu G, Chhangawala S, Cocco E, Razavi P, Cai Y, Otto JE, Ferrando L, Selenica P, Ladewig E, Chan C, Da Cruz Paula A, Witkin M, Cheng Y, Park J, Serna-Tamayo C, Zhao H, Wu F, Sallaku M, Qu X, Zhao A, Collings CK, D'Avino AR, Jhaveri K, Koche R, Levine RL, Reis-Filho JS, Kadoch C, Scaltriti M, Leslie CS, Baselga J, Toska E. Xu G, et al. Nat Genet. 2020 Feb;52(2):198-207. doi: 10.1038/s41588-019-0554-0. Epub 2020 Jan 13. Nat Genet. 2020. PMID: 31932695 Free PMC article.

10

FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer.

Arruabarrena-Aristorena A, Maag JLV, Kittane S, Cai Y, Karthaus WR, Ladewig E, Park J, Kannan S, Ferrando L, Cocco E, Ho SY, Tan DS, Sallaku M, Wu F, Acevedo B, Selenica P, Ross DS, Witkin M, Sawyers CL, Reis-Filho JS, Verma CS, Jauch R, Koche R, Baselga J, Razavi P, Toska E, Scaltriti M. Arruabarrena-Aristorena A, et al. Cancer Cell. 2020 Oct 12;38(4):534-550.e9. doi: 10.1016/j.ccell.2020.08.003. Epub 2020 Sep 3. Cancer Cell. 2020. PMID: 32888433 Free PMC article.

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