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Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Caescu CI, Hansen J, Crockett B, Xiao W, Arnaud P, Spronck B, Weinberg A, Hashimoto T, Murtada SI, Borkar R, Gallo JM, Jondeau G, Boileau C, Humphrey JD, He JC, Iyengar R, Ramirez F. Caescu CI, et al. Among authors: spronck b. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2483-2493. doi: 10.1161/ATVBAHA.121.316464. Epub 2021 Jul 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 34320838 Free PMC article.
Systems pharmacology-based integration of human and mouse data for drug repurposing to treat thoracic aneurysms.
Hansen J, Galatioto J, Caescu CI, Arnaud P, Calizo RC, Spronck B, Murtada SI, Borkar R, Weinberg A, Azeloglu EU, Bintanel-Morcillo M, Gallo JM, Humphrey JD, Jondeau G, Boileau C, Ramirez F, Iyengar R. Hansen J, et al. Among authors: spronck b. JCI Insight. 2019 Jun 6;4(11):e127652. doi: 10.1172/jci.insight.127652. eCollection 2019 Jun 6. JCI Insight. 2019. PMID: 31167969 Free PMC article.
Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity.
Salarian M, Ghim M, Toczek J, Han J, Weiss D, Spronck B, Ramachandra AB, Jung JJ, Kukreja G, Zhang J, Lakheram D, Kim SK, Humphrey JD, Sadeghi MM. Salarian M, et al. Among authors: spronck b. Circ Res. 2023 Feb 17;132(4):432-448. doi: 10.1161/CIRCRESAHA.122.322096. Epub 2023 Jan 24. Circ Res. 2023. PMID: 36691905 Free PMC article.
Smooth Muscle Cell Death Drives an Osteochondrogenic Phenotype and Severe Proximal Vascular Disease in Progeria.
Murtada SI, Kawamura Y, Cavinato C, Wang M, Ramachandra AB, Spronck B, Tellides G, Humphrey JD. Murtada SI, et al. Among authors: spronck b. bioRxiv [Preprint]. 2023 Jan 11:2023.01.10.523266. doi: 10.1101/2023.01.10.523266. bioRxiv. 2023. Update in: Biomech Model Mechanobiol. 2023 Aug;22(4):1333-1347. doi: 10.1007/s10237-023-01722-5 PMID: 36711514 Free PMC article. Updated. Preprint.
88 results