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Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Caescu CI, Hansen J, Crockett B, Xiao W, Arnaud P, Spronck B, Weinberg A, Hashimoto T, Murtada SI, Borkar R, Gallo JM, Jondeau G, Boileau C, Humphrey JD, He JC, Iyengar R, Ramirez F. Caescu CI, et al. Among authors: humphrey jd. Arterioscler Thromb Vasc Biol. 2021 Sep;41(9):2483-2493. doi: 10.1161/ATVBAHA.121.316464. Epub 2021 Jul 29. Arterioscler Thromb Vasc Biol. 2021. PMID: 34320838 Free PMC article.
Pharmacologically Improved Contractility Protects Against Aortic Dissection in Mice With Disrupted Transforming Growth Factor-β Signaling Despite Compromised Extracellular Matrix Properties.
Ferruzzi J, Murtada SI, Li G, Jiao Y, Uman S, Ting MY, Tellides G, Humphrey JD. Ferruzzi J, et al. Among authors: humphrey jd. Arterioscler Thromb Vasc Biol. 2016 May;36(5):919-27. doi: 10.1161/ATVBAHA.116.307436. Epub 2016 Mar 17. Arterioscler Thromb Vasc Biol. 2016. PMID: 26988590 Free PMC article.
mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice.
Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G. Jiao Y, et al. Among authors: humphrey jd. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1657-1666. doi: 10.1161/ATVBAHA.117.309653. Epub 2017 Jul 27. Arterioscler Thromb Vasc Biol. 2017. PMID: 28751568 Free PMC article.
Central artery stiffness and thoracic aortopathy.
Humphrey JD, Tellides G. Humphrey JD, et al. Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H169-H182. doi: 10.1152/ajpheart.00205.2018. Epub 2018 Nov 9. Am J Physiol Heart Circ Physiol. 2019. PMID: 30412443 Free PMC article. Review.
404 results