Sheng C - Search Results

1

Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery.

Dong G, Ding Y, He S, Sheng C. Dong G, et al. Among authors: sheng c. J Med Chem. 2021 Aug 12;64(15):10606-10620. doi: 10.1021/acs.jmedchem.1c00895. Epub 2021 Jul 28. J Med Chem. 2021. PMID: 34319094 Review.

2

Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.

Sheng C, Zhang W, Ji H, Zhang M, Song Y, Xu H, Zhu J, Miao Z, Jiang Q, Yao J, Zhou Y, Zhu J, Lü J. Sheng C, et al. J Med Chem. 2006 Apr 20;49(8):2512-25. doi: 10.1021/jm051211n. J Med Chem. 2006. PMID: 16610794

3

3D-QSAR and molecular docking studies on benzothiazole derivatives as Candida albicans N-myristoyltransferase inhibitors.

Sheng C, Zhu J, Zhang W, Zhang M, Ji H, Song Y, Xu H, Yao J, Miao Z, Zhou Y, Zhu J, Lü J. Sheng C, et al. Eur J Med Chem. 2007 Apr;42(4):477-86. doi: 10.1016/j.ejmech.2006.11.001. Epub 2006 Nov 18. Eur J Med Chem. 2007. PMID: 17349719

4

Construction of a three-dimensional pharmacophore for Bcl-2 inhibitors by flexible docking and the multiple copy simultaneous search method.

Zheng CH, Zhou YJ, Zhu J, Ji HT, Chen J, Li YW, Sheng CQ, Lu JG, Jiang JH, Tang H, Song YL. Zheng CH, et al. Bioorg Med Chem. 2007 Oct 1;15(19):6407-17. doi: 10.1016/j.bmc.2007.06.052. Epub 2007 Jul 4. Bioorg Med Chem. 2007. PMID: 17629704

5

New homocamptothecins: synthesis, antitumor activity, and molecular modeling.

Miao Z, Sheng C, Zhang W, Ji H, Zhang J, Shao L, You L, Zhang M, Yao J, Che X. Miao Z, et al. Among authors: sheng c. Bioorg Med Chem. 2008 Feb 1;16(3):1493-510. doi: 10.1016/j.bmc.2007.10.046. Epub 2007 Oct 22. Bioorg Med Chem. 2008. PMID: 18207748

6

Homology modeling and molecular dynamics simulation of N-myristoyltransferase from protozoan parasites: active site characterization and insights into rational inhibitor design.

Sheng C, Ji H, Miao Z, Che X, Yao J, Wang W, Dong G, Guo W, Lü J, Zhang W. Sheng C, et al. J Comput Aided Mol Des. 2009 Jun;23(6):375-89. doi: 10.1007/s10822-009-9267-2. Epub 2009 Apr 16. J Comput Aided Mol Des. 2009. PMID: 19370313

7

Three-dimensional model of lanosterol 14 alpha-demethylase from Cryptococcus neoformans: active-site characterization and insights into azole binding.

Sheng C, Miao Z, Ji H, Yao J, Wang W, Che X, Dong G, Lü J, Guo W, Zhang W. Sheng C, et al. Antimicrob Agents Chemother. 2009 Aug;53(8):3487-95. doi: 10.1128/AAC.01630-08. Epub 2009 May 26. Antimicrob Agents Chemother. 2009. PMID: 19470512 Free PMC article.

8

New azoles with potent antifungal activity: design, synthesis and molecular docking.

Che X, Sheng C, Wang W, Cao Y, Xu Y, Ji H, Dong G, Miao Z, Yao J, Zhang W. Che X, et al. Among authors: sheng c. Eur J Med Chem. 2009 Oct;44(10):4218-26. doi: 10.1016/j.ejmech.2009.05.018. Epub 2009 May 24. Eur J Med Chem. 2009. PMID: 19539408

9

Evolutionary trace analysis of CYP51 family: implication for site-directed mutagenesis and novel antifungal drug design.

Sheng C, Chen S, Ji H, Dong G, Che X, Wang W, Miao Z, Yao J, Lü J, Guo W, Zhang W. Sheng C, et al. J Mol Model. 2010 Feb;16(2):279-84. doi: 10.1007/s00894-009-0527-9. Epub 2009 Jul 11. J Mol Model. 2010. PMID: 19593597

10

Discovery of highly potent novel antifungal azoles by structure-based rational design.

Wang W, Sheng C, Che X, Ji H, Cao Y, Miao Z, Yao J, Zhang W. Wang W, et al. Among authors: sheng c. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5965-9. doi: 10.1016/j.bmcl.2009.07.144. Epub 2009 Aug 3. Bioorg Med Chem Lett. 2009. PMID: 19748782

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