Manning BD - Search Results

1

Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.

Byles V, Cormerais Y, Kalafut K, Barrera V, Hughes Hallett JE, Sui SH, Asara JM, Adams CM, Hoxhaj G, Ben-Sahra I, Manning BD. Byles V, et al. Among authors: manning bd. Mol Metab. 2021 Nov;53:101309. doi: 10.1016/j.molmet.2021.101309. Epub 2021 Jul 23. Mol Metab. 2021. PMID: 34303878 Free PMC article.

2

Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis.

Ozcan U, Ozcan L, Yilmaz E, Düvel K, Sahin M, Manning BD, Hotamisligil GS. Ozcan U, et al. Among authors: manning bd. Mol Cell. 2008 Mar 14;29(5):541-51. doi: 10.1016/j.molcel.2007.12.023. Mol Cell. 2008. PMID: 18342602 Free PMC article.

3

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2.

Huang J, Dibble CC, Matsuzaki M, Manning BD. Huang J, et al. Among authors: manning bd. Mol Cell Biol. 2008 Jun;28(12):4104-15. doi: 10.1128/MCB.00289-08. Epub 2008 Apr 14. Mol Cell Biol. 2008. PMID: 18411301 Free PMC article.

4

Insulin stimulates adipogenesis through the Akt-TSC2-mTORC1 pathway.

Zhang HH, Huang J, Düvel K, Boback B, Wu S, Squillace RM, Wu CL, Manning BD. Zhang HH, et al. Among authors: manning bd. PLoS One. 2009 Jul 10;4(7):e6189. doi: 10.1371/journal.pone.0006189. PLoS One. 2009. PMID: 19593385 Free PMC article.

5

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.

Dibble CC, Asara JM, Manning BD. Dibble CC, et al. Among authors: manning bd. Mol Cell Biol. 2009 Nov;29(21):5657-70. doi: 10.1128/MCB.00735-09. Epub 2009 Aug 31. Mol Cell Biol. 2009. PMID: 19720745 Free PMC article.

6

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S, Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, Manning BD. Düvel K, et al. Among authors: manning bd. Mol Cell. 2010 Jul 30;39(2):171-83. doi: 10.1016/j.molcel.2010.06.022. Mol Cell. 2010. PMID: 20670887 Free PMC article.

7

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis.

Howell JJ, Manning BD. Howell JJ, et al. Among authors: manning bd. Trends Endocrinol Metab. 2011 Mar;22(3):94-102. doi: 10.1016/j.tem.2010.12.003. Epub 2011 Jan 25. Trends Endocrinol Metab. 2011. PMID: 21269838 Free PMC article. Review.

8

mTOR links oncogenic signaling to tumor cell metabolism.

Yecies JL, Manning BD. Yecies JL, et al. Among authors: manning bd. J Mol Med (Berl). 2011 Mar;89(3):221-8. doi: 10.1007/s00109-011-0726-6. Epub 2011 Feb 8. J Mol Med (Berl). 2011. PMID: 21301797 Review.

9

Transcriptional control of cellular metabolism by mTOR signaling.

Yecies JL, Manning BD. Yecies JL, et al. Among authors: manning bd. Cancer Res. 2011 Apr 15;71(8):2815-20. doi: 10.1158/0008-5472.CAN-10-4158. Epub 2011 Apr 12. Cancer Res. 2011. PMID: 21487041 Free PMC article.

10

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD. Yecies JL, et al. Among authors: manning bd. Cell Metab. 2011 Jul 6;14(1):21-32. doi: 10.1016/j.cmet.2011.06.002. Cell Metab. 2011. PMID: 21723501 Free PMC article.

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