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Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization.
Jamroskovic J, Doimo M, Chand K, Obi I, Kumar R, Brännström K, Hedenström M, Nath Das R, Akhunzianov A, Deiana M, Kasho K, Sulis Sato S, Pourbozorgi PL, Mason JE, Medini P, Öhlund D, Wanrooij S, Chorell E, Sabouri N. Jamroskovic J, et al. Among authors: obi i. J Am Chem Soc. 2020 Feb 12;142(6):2876-2888. doi: 10.1021/jacs.9b11232. Epub 2020 Jan 28. J Am Chem Soc. 2020. PMID: 31990532 Free PMC article.
A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression.
Deiana M, Andrés Castán JM, Josse P, Kahsay A, Sánchez DP, Morice K, Gillet N, Ravindranath R, Patel AK, Sengupta P, Obi I, Rodriguez-Marquez E, Khrouz L, Dumont E, Abad Galán L, Allain M, Walker B, Ahn HS, Maury O, Blanchard P, Le Bahers T, Öhlund D, von Hofsten J, Monnereau C, Cabanetos C, Sabouri N. Deiana M, et al. Among authors: obi i. Nucleic Acids Res. 2023 Jul 7;51(12):6264-6285. doi: 10.1093/nar/gkad365. Nucleic Acids Res. 2023. PMID: 37191066 Free PMC article.
69 results