Wiemer DF - Search Results

1

Impact of α-modifications on the activity of triazole bisphosphonates as geranylgeranyl diphosphate synthase inhibitors.

Fairweather AER, Goetz DB, Schroeder CM, Bhuiyan NH, Varney ML, Wiemer DF, Holstein SA. Fairweather AER, et al. Among authors: wiemer df. Bioorg Med Chem. 2021 Aug 15;44:116307. doi: 10.1016/j.bmc.2021.116307. Epub 2021 Jul 11. Bioorg Med Chem. 2021. PMID: 34298413 Free PMC article.

2

Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase.

Holstein SA, Cermak DM, Wiemer DF, Lewis K, Hohl RJ. Holstein SA, et al. Among authors: wiemer df. Bioorg Med Chem. 1998 Jun;6(6):687-94. doi: 10.1016/s0968-0896(98)00034-0. Bioorg Med Chem. 1998. PMID: 9681134

3

Synthesis of phosphonate derivatives of uridine, cytidine, and cytosine arabinoside.

Jung KY, Hohl RJ, Wiemer AJ, Wiemer DF. Jung KY, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem. 2000 Oct;8(10):2501-9. doi: 10.1016/s0968-0896(00)00183-8. Bioorg Med Chem. 2000. PMID: 11058045

4

2-(Acyloxy)ethylphosphonate analogues of prenyl pyrophosphates: synthesis and biological characterization.

Cermak DM, Wiemer DF, Lewis K, Hohl RJ. Cermak DM, et al. Among authors: wiemer df. Bioorg Med Chem. 2000 Dec;8(12):2729-37. doi: 10.1016/s0968-0896(00)00212-1. Bioorg Med Chem. 2000. PMID: 11131164

5

Isoprenoid pyrophosphate analogues regulate expression of Ras-related proteins.

Holstein SA, Wohlford-Lenane CL, Wiemer DF, Hohl RJ. Holstein SA, et al. Among authors: wiemer df. Biochemistry. 2003 Apr 22;42(15):4384-91. doi: 10.1021/bi027227m. Biochemistry. 2003. PMID: 12693933

6

Tripeptide probes for tripeptidyl protease I production via gene transfer.

Kim M, Mao Q, Davidson BL, Wiemer DF. Kim M, et al. Among authors: wiemer df. J Med Chem. 2003 Apr 24;46(9):1603-8. doi: 10.1021/jm020525x. J Med Chem. 2003. PMID: 12699378

7

Synthesis and activity of fluorescent isoprenoid pyrophosphate analogues.

Kim M, Kleckley TS, Wiemer AJ, Holstein SA, Hohl RJ, Wiemer DF. Kim M, et al. Among authors: wiemer aj, wiemer df. J Org Chem. 2004 Nov 26;69(24):8186-93. doi: 10.1021/jo049101w. J Org Chem. 2004. PMID: 15549786

8

Synthesis and structure-activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity.

Neighbors JD, Salnikova MS, Beutler JA, Wiemer DF. Neighbors JD, et al. Among authors: wiemer df. Bioorg Med Chem. 2006 Mar 15;14(6):1771-84. doi: 10.1016/j.bmc.2005.10.025. Epub 2005 Nov 14. Bioorg Med Chem. 2006. PMID: 16290161

9

Synthesis and biological activity of isoprenoid bisphosphonates.

Shull LW, Wiemer AJ, Hohl RJ, Wiemer DF. Shull LW, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem. 2006 Jun 15;14(12):4130-6. doi: 10.1016/j.bmc.2006.02.010. Epub 2006 Mar 6. Bioorg Med Chem. 2006. PMID: 16517172

10

Total synthesis of (R,R,R)- and (S,S,S)-schweinfurthin F: differences of bioactivity in the enantiomeric series.

Mente NR, Wiemer AJ, Neighbors JD, Beutler JA, Hohl RJ, Wiemer DF. Mente NR, et al. Among authors: wiemer aj, wiemer df. Bioorg Med Chem Lett. 2007 Feb 15;17(4):911-5. doi: 10.1016/j.bmcl.2006.11.096. Epub 2006 Dec 12. Bioorg Med Chem Lett. 2007. PMID: 17236766

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