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Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.
Rashid ST, Corbineau S, Hannan N, Marciniak SJ, Miranda E, Alexander G, Huang-Doran I, Griffin J, Ahrlund-Richter L, Skepper J, Semple R, Weber A, Lomas DA, Vallier L. Rashid ST, et al. Among authors: vallier l. J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25. J Clin Invest. 2010. PMID: 20739751 Free PMC article.
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells.
Yusa K, Rashid ST, Strick-Marchand H, Varela I, Liu PQ, Paschon DE, Miranda E, Ordóñez A, Hannan NR, Rouhani FJ, Darche S, Alexander G, Marciniak SJ, Fusaki N, Hasegawa M, Holmes MC, Di Santo JP, Lomas DA, Bradley A, Vallier L. Yusa K, et al. Among authors: vallier l. Nature. 2011 Oct 12;478(7369):391-4. doi: 10.1038/nature10424. Nature. 2011. PMID: 21993621 Free PMC article.
Generation of multipotent foregut stem cells from human pluripotent stem cells.
Hannan NR, Fordham RP, Syed YA, Moignard V, Berry A, Bautista R, Hanley NA, Jensen KB, Vallier L. Hannan NR, et al. Among authors: vallier l. Stem Cell Reports. 2013 Oct 10;1(4):293-306. doi: 10.1016/j.stemcr.2013.09.003. eCollection 2013. Stem Cell Reports. 2013. PMID: 24319665 Free PMC article.
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
Baxter M, Withey S, Harrison S, Segeritz CP, Zhang F, Atkinson-Dell R, Rowe C, Gerrard DT, Sison-Young R, Jenkins R, Henry J, Berry AA, Mohamet L, Best M, Fenwick SW, Malik H, Kitteringham NR, Goldring CE, Piper Hanley K, Vallier L, Hanley NA. Baxter M, et al. Among authors: vallier l. J Hepatol. 2015 Mar;62(3):581-9. doi: 10.1016/j.jhep.2014.10.016. Epub 2014 Oct 18. J Hepatol. 2015. PMID: 25457200 Free PMC article.
188 results