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Multisite investigation of strategies for the clinical implementation of pre-emptive pharmacogenetic testing.
Duarte JD, Dalton R, Elchynski AL, Smith DM, Cicali EJ, Lee JC, Duong BQ, Petry NJ, Aquilante CL, Beitelshees AL, Empey PE, Johnson JA, Obeng AO, Pasternak AL, Pratt VM, Ramsey LB, Tuteja S, Van Driest SL, Wiisanen K, Hicks JK, Cavallari LH; IGNITE Network Pharmacogenetics Working Group. Duarte JD, et al. Among authors: dalton r. Genet Med. 2021 Dec;23(12):2335-2341. doi: 10.1038/s41436-021-01269-9. Epub 2021 Jul 19. Genet Med. 2021. PMID: 34282303 Free PMC article.
Transfer learning enables prediction of CYP2D6 haplotype function.
McInnes G, Dalton R, Sangkuhl K, Whirl-Carrillo M, Lee SB, Tsao PS, Gaedigk A, Altman RB, Woodahl EL. McInnes G, et al. Among authors: dalton r. PLoS Comput Biol. 2020 Nov 2;16(11):e1008399. doi: 10.1371/journal.pcbi.1008399. eCollection 2020 Nov. PLoS Comput Biol. 2020. PMID: 33137098 Free PMC article.
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.
Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Wong LH, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, Gaedigk A, Thummel KE, Woodahl EL. Dalton R, et al. Clin Transl Sci. 2020 Jan;13(1):147-156. doi: 10.1111/cts.12695. Epub 2019 Oct 25. Clin Transl Sci. 2020. PMID: 31536170 Free PMC article.
P-Glycoprotein Transport of Neurotoxic Pesticides.
Lacher SE, Skagen K, Veit J, Dalton R, Woodahl EL. Lacher SE, et al. Among authors: dalton r. J Pharmacol Exp Ther. 2015 Oct;355(1):99-107. doi: 10.1124/jpet.115.226373. Epub 2015 Aug 13. J Pharmacol Exp Ther. 2015. PMID: 26272936 Free PMC article.
Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function.
Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Fohner AE, et al. Among authors: dalton r. Clin Transl Sci. 2021 Jul;14(4):1292-1302. doi: 10.1111/cts.12970. Epub 2021 Jan 27. Clin Transl Sci. 2021. PMID: 33503331 Free PMC article.
848 results