Nacy CA - Search Results

1

Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate.

Malwal SR, Zimmerman MD, Alvarez N, Sarathy JP, Dartois V, Nacy CA, Oldfield E. Malwal SR, et al. Among authors: nacy ca. ACS Infect Dis. 2021 Aug 13;7(8):2492-2507. doi: 10.1021/acsinfecdis.1c00259. Epub 2021 Jul 19. ACS Infect Dis. 2021. PMID: 34279904 Free PMC article.

2

Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits.

Egbelowo O, Sarathy JP, Gausi K, Zimmerman MD, Wang H, Wijnant GJ, Kaya F, Gengenbacher M, Van N, Degefu Y, Nacy C, Aldridge BB, Carter CL, Denti P, Dartois V. Egbelowo O, et al. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0002421. doi: 10.1128/AAC.00024-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34228540 Free PMC article.

3

Anti-tuberculosis drug therapy in mice of different inbred strains.

Nikonenko BV, Einck L, Nacy CA. Nikonenko BV, et al. Among authors: nacy ca. Infect Genet Evol. 2010 Oct;10(7):1151-4. doi: 10.1016/j.meegid.2010.07.014. Epub 2010 Jul 22. Infect Genet Evol. 2010. PMID: 20655396

4

Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action.

Sacksteder KA, Protopopova M, Barry CE 3rd, Andries K, Nacy CA. Sacksteder KA, et al. Among authors: nacy ca. Future Microbiol. 2012 Jul;7(7):823-37. doi: 10.2217/fmb.12.56. Future Microbiol. 2012. PMID: 22827305 Free PMC article. Review.

5

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines.

Protopopova M, Hanrahan C, Nikonenko B, Samala R, Chen P, Gearhart J, Einck L, Nacy CA. Protopopova M, et al. Among authors: nacy ca. J Antimicrob Chemother. 2005 Nov;56(5):968-74. doi: 10.1093/jac/dki319. Epub 2005 Sep 19. J Antimicrob Chemother. 2005. PMID: 16172107

6

Drug therapy of experimental tuberculosis (TB): improved outcome by combining SQ109, a new diamine antibiotic, with existing TB drugs.

Nikonenko BV, Protopopova M, Samala R, Einck L, Nacy CA. Nikonenko BV, et al. Among authors: nacy ca. Antimicrob Agents Chemother. 2007 Apr;51(4):1563-5. doi: 10.1128/AAC.01326-06. Epub 2007 Jan 22. Antimicrob Agents Chemother. 2007. PMID: 17242141 Free PMC article.

7

In vitro interactions between new antitubercular drug candidates SQ109 and TMC207.

Reddy VM, Einck L, Andries K, Nacy CA. Reddy VM, et al. Among authors: nacy ca. Antimicrob Agents Chemother. 2010 Jul;54(7):2840-6. doi: 10.1128/AAC.01601-09. Epub 2010 Apr 12. Antimicrob Agents Chemother. 2010. PMID: 20385864 Free PMC article.

8

SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro.

Reddy VM, Dubuisson T, Einck L, Wallis RS, Jakubiec W, Ladukto L, Campbell S, Nacy CA. Reddy VM, et al. Among authors: nacy ca. J Antimicrob Chemother. 2012 May;67(5):1163-6. doi: 10.1093/jac/dkr589. Epub 2012 Jan 17. J Antimicrob Chemother. 2012. PMID: 22258923

9

Synergistic interactions of SQ109, a new ethylene diamine, with front-line antitubercular drugs in vitro.

Chen P, Gearhart J, Protopopova M, Einck L, Nacy CA. Chen P, et al. Among authors: nacy ca. J Antimicrob Chemother. 2006 Aug;58(2):332-7. doi: 10.1093/jac/dkl227. Epub 2006 Jun 3. J Antimicrob Chemother. 2006. PMID: 16751637

10

Detection of active tuberculosis by an MPB-64 transdermal patch: a field study.

Nakamura RM, Einck L, Velmonte MA, Kawajiri K, Ang CF, Delasllagas CE, Nacy CA. Nakamura RM, et al. Among authors: nacy ca. Scand J Infect Dis. 2001;33(6):405-7. doi: 10.1080/00365540152029846. Scand J Infect Dis. 2001. PMID: 11450857

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