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Prediction of the drug-drug interaction potential of the α1-acid glycoprotein bound, CYP3A4/CYP2C9 metabolized oncology drug, erdafitinib.
De Zwart L, Snoeys J, Jacobs F, Li LY, Poggesi I, Verboven P, Goris I, Scheers E, Wynant I, Monshouwer M, Mamidi RNVS. De Zwart L, et al. Among authors: scheers e. CPT Pharmacometrics Syst Pharmacol. 2021 Sep;10(9):1107-1118. doi: 10.1002/psp4.12682. Epub 2021 Aug 11. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 34273250 Free PMC article.
In vitro metabolism of canagliflozin in human liver, kidney, intestine microsomes, and recombinant uridine diphosphate glucuronosyltransferases (UGT) and the effect of genetic variability of UGT enzymes on the pharmacokinetics of canagliflozin in humans.
Francke S, Mamidi RN, Solanki B, Scheers E, Jadwin A, Favis R, Devineni D. Francke S, et al. Among authors: scheers e. J Clin Pharmacol. 2015 Sep;55(9):1061-72. doi: 10.1002/jcph.506. Epub 2015 May 20. J Clin Pharmacol. 2015. PMID: 25827774
Metabolism and excretion of canagliflozin in mice, rats, dogs, and humans.
Mamidi RN, Cuyckens F, Chen J, Scheers E, Kalamaridis D, Lin R, Silva J, Sha S, Evans DC, Kelley MF, Devineni D, Johnson MD, Lim HK. Mamidi RN, et al. Among authors: scheers e. Drug Metab Dispos. 2014 May;42(5):903-16. doi: 10.1124/dmd.113.056440. Epub 2014 Feb 25. Drug Metab Dispos. 2014. PMID: 24568888 Clinical Trial.
Outcomes of endometrial cancer prevention strategies in patients with Lynch syndrome: a nationwide cohort study in the Netherlands.
Eikenboom EL, van Leeuwen L, Groenendijk F, Woolderink JM, Van Altena AM, Van Leerdam ME, Spaander MCW, van Doorn HC, Wagner A; collaborative investigators from the Dutch Foundation for Detection of Hereditary Tumors. Eikenboom EL, et al. EClinicalMedicine. 2024 Dec 21;79:103006. doi: 10.1016/j.eclinm.2024.103006. eCollection 2025 Jan. EClinicalMedicine. 2024. PMID: 39816931 Free PMC article.
A stable hepatitis D virus-producing cell line for host target and drug discovery.
Bach C, Lucifora J, Delphin M, Heydmann L, Heuschkel MJ, Pons C, Goto K, Scheers E, Schuster C, Durantel D, Pauwels F, Baumert TF, Verrier ER. Bach C, et al. Among authors: scheers e. Antiviral Res. 2023 Jan;209:105477. doi: 10.1016/j.antiviral.2022.105477. Epub 2022 Nov 26. Antiviral Res. 2023. PMID: 36511319 Free article.
24 results