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A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
Pino M, Abid T, Pereira Ribeiro S, Edara VV, Floyd K, Smith JC, Latif MB, Pacheco-Sanchez G, Dutta D, Wang S, Gumber S, Kirejczyk S, Cohen J, Stammen RL, Jean SM, Wood JS, Connor-Stroud F, Pollet J, Chen WH, Wei J, Zhan B, Lee J, Liu Z, Strych U, Shenvi N, Easley K, Weiskopf D, Sette A, Pollara J, Mielke D, Gao H, Eisel N, LaBranche CC, Shen X, Ferrari G, Tomaras GD, Montefiori DC, Sekaly RP, Vanderford TH, Tomai MA, Fox CB, Suthar MS, Kozlowski PA, Hotez PJ, Paiardini M, Bottazzi ME, Kasturi SP. Pino M, et al. Among authors: chen wh. Sci Immunol. 2021 Jul 15;6(61):eabh3634. doi: 10.1126/sciimmunol.abh3634. Sci Immunol. 2021. PMID: 34266981 Free PMC article.
Biophysical characterization of VEGF-aHt DNA aptamer interactions.
Kanakaraj I, Chen WH, Poongavanam M, Dhamane S, Stagg LJ, Ladbury JE, Kourentzi K, Strych U, Willson RC. Kanakaraj I, et al. Among authors: chen wh. Int J Biol Macromol. 2013 Jun;57:69-75. doi: 10.1016/j.ijbiomac.2013.02.016. Epub 2013 Mar 5. Int J Biol Macromol. 2013. PMID: 23470436
Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate.
Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ. Chen WH, et al. J Pharm Sci. 2017 Aug;106(8):1961-1970. doi: 10.1016/j.xphs.2017.04.037. Epub 2017 Apr 26. J Pharm Sci. 2017. PMID: 28456726 Free PMC article.
A method to probe protein structure from UV absorbance spectra.
Biter AB, Pollet J, Chen WH, Strych U, Hotez PJ, Bottazzi ME. Biter AB, et al. Among authors: chen wh. Anal Biochem. 2019 Dec 15;587:113450. doi: 10.1016/j.ab.2019.113450. Epub 2019 Sep 21. Anal Biochem. 2019. PMID: 31550438
The SARS-CoV-2 Vaccine Pipeline: an Overview.
Chen WH, Strych U, Hotez PJ, Bottazzi ME. Chen WH, et al. Curr Trop Med Rep. 2020;7(2):61-64. doi: 10.1007/s40475-020-00201-6. Epub 2020 Mar 3. Curr Trop Med Rep. 2020. PMID: 32219057 Free PMC article. Review.
2,111 results