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CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity.
Liang YY, Bacanu S, Sreekumar L, Ramos AD, Dai L, Michaelis M, Cinatl J, Seki T, Cao Y, Coffill CR, Lane DP, Prabhu N, Nordlund P. Liang YY, et al. Among authors: bacanu s. Cell Chem Biol. 2022 Apr 21;29(4):572-585.e8. doi: 10.1016/j.chembiol.2021.06.007. Epub 2021 Jul 16. Cell Chem Biol. 2022. PMID: 34265272 Free article.
CETSA-based target engagement of taxanes as biomarkers for efficacy and resistance.
Langebäck A, Bacanu S, Laursen H, Mout L, Seki T, Erkens-Schulze S, Ramos AD, Berggren A, Cao Y, Hartman J, van Weerden W, Bergh J, Nordlund P, Lööf S. Langebäck A, et al. Among authors: bacanu s. Sci Rep. 2019 Dec 18;9(1):19384. doi: 10.1038/s41598-019-55526-8. Sci Rep. 2019. PMID: 31852908 Free PMC article.
Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery.
Ramos AD, Liang YY, Surova O, Bacanu S, Gerault MA, Mandal T, Ceder S, Langebäck A, Österroos A, Ward GA, Bergh J, Wiman KG, Lehmann S, Prabhu N, Lööf S, Nordlund P. Ramos AD, et al. Among authors: bacanu s. Cell Rep. 2024 Oct 22;43(10):114784. doi: 10.1016/j.celrep.2024.114784. Epub 2024 Oct 3. Cell Rep. 2024. PMID: 39365699 Free article.
Genetic liability estimated from large-scale family data improves genetic prediction, risk score profiling, and gene mapping for major depression.
Dybdahl Krebs M, Georgii Hellberg KL, Lundberg M, Appadurai V, Ohlsson H, Pedersen E, Steinbach J, Matthews J, Border R, LaBianca S, Calle X, Meijsen JJ; iPSYCH Study Consortium,; Ingason A, Buil A, Vilhjálmsson BJ, Flint J, Bacanu SA, Cai N, Dahl A, Zaitlen N, Werge T, Kendler KS, Schork AJ. Dybdahl Krebs M, et al. Among authors: bacanu sa. Am J Hum Genet. 2024 Nov 7;111(11):2494-2509. doi: 10.1016/j.ajhg.2024.09.009. Epub 2024 Oct 28. Am J Hum Genet. 2024. PMID: 39471805
Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
Strom NI, Verhulst B, Bacanu SA, Cheesman R, Purves KL, Gedik H, Mitchell BL, Kwong AS, Faucon AB, Singh K, Medland S, Colodro-Conde L, Krebs K, Hoffmann P, Herms S, Gehlen J, Ripke S, Awasthi S, Palviainen T, Tasanko EM, Peterson RE, Adkins DE, Shabalin AA, Adams MJ, Iveson MH, Campbell A, Thomas LF, Winsvold BS, Drange OK, Børte S, Ter Kuile AR, Nguyen TH, Meier SM, Corfield EC, Hannigan L, Levey DF, Czamara D, Weber H, Choi KW, Pistis G, Couvy-Duchesne B, Van der Auwera S, Teumer A, Karlsson R, Garcia-Argibay M, Lee D, Wang R, Bjerkeset O, Stordal E, Bäckmann J, Salum GA, Zai CC, Kennedy JL, Zai G, Tiwari AK, Heilmann-Heimbach S, Schmidt B, Kaprio J, Kennedy MM, Boden J, Havdahl A, Middeldorp CM, Lopes FL, Akula N, McMahon FJ, Binder EB, Fehm L, Ströhle A, Castelao E, Tiemeier H, Stein DJ, Whiteman D, Olsen C, Fuller Z, Wang X, Wray NR, Byrne EM, Lewis G, Timpson NJ, Davis LK, Hickie IB, Gillespie NA, Milani L, Schumacher J, Woldbye DP, Forstner AJ, Nöthen MM, Hovatta I, Horwood J, Copeland WE, Maes HH, McIntosh AM, Andreassen OA, Zwart JA, Mors O, Børglum AD, Mortensen PB, Ask H, Reichborn-Kjennerud T, Najman JM, Stein MB, Gelernter J, Milaneschi Y, Penninx BW, Boomsma … See abstract for full author list ➔ Strom NI, et al. Among authors: bacanu sa. medRxiv [Preprint]. 2024 Jul 5:2024.07.03.24309466. doi: 10.1101/2024.07.03.24309466. medRxiv. 2024. PMID: 39006447 Free PMC article. Preprint.
182 results