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Page 1
Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with Schizophrenia.
Reichard HA, Schiffer HH, Monenschein H, Atienza JM, Corbett G, Skaggs AW, Collia DR, Ray WJ, Serrats J, Bliesath J, Kaushal N, Lam BP, Amador-Arjona A, Rahbaek L, McConn DJ, Mulligan VJ, Brice N, Gaskin PLR, Cilia J, Hitchcock S. Reichard HA, et al. Among authors: gaskin plr. J Med Chem. 2021 Aug 12;64(15):11527-11542. doi: 10.1021/acs.jmedchem.1c00820. Epub 2021 Jul 14. J Med Chem. 2021. PMID: 34260228
Ventromedial prefrontal area 14 provides opposing regulation of threat and reward-elicited responses in the common marmoset.
Stawicka ZM, Massoudi R, Horst NK, Koda K, Gaskin PLR, Alexander L, Santangelo AM, McIver L, Cockcroft GJ, Wood CM, Roberts AC. Stawicka ZM, et al. Among authors: gaskin plr. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25116-25127. doi: 10.1073/pnas.2009657117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958652 Free PMC article.
Luvadaxistat: A Novel Potent and Selective D-Amino Acid Oxidase Inhibitor Improves Cognitive and Social Deficits in Rodent Models for Schizophrenia.
Fradley R, Goetghebeur P, Miller D, Burley R, Almond S, Gruart I Massó A, Delgado García JM, Zhu B, Howley E, Neill JC, Grayson B, Gaskin P, Carlton M, Gray I, Serrats J, Davies CH. Fradley R, et al. Neurochem Res. 2023 Oct;48(10):3027-3041. doi: 10.1007/s11064-023-03956-2. Epub 2023 Jun 8. Neurochem Res. 2023. PMID: 37289348 Free PMC article.
Correction to: Luvadaxistat: A Novel Potent and Selective D-Amino Acid Oxidase Inhibitor Improves Cognitive and Social Deficits in Rodent Models for Schizophrenia.
Fradley R, Goetghebeur P, Miller D, Burley R, Almond S, Gruart I Massó A, Delgado García JM, Zhu B, Howley E, Neill JC, Grayson B, Gaskin P, Carlton M, Gray I, Serrats J, Davies CH. Fradley R, et al. Neurochem Res. 2023 Nov;48(11):3472. doi: 10.1007/s11064-023-03987-9. Neurochem Res. 2023. PMID: 37440119 Free PMC article. No abstract available.
Down-Regulation of Hippocampal Genes Regulating Dopaminergic, GABAergic, and Glutamatergic Function Following Combined Neonatal Phencyclidine and Post-Weaning Social Isolation of Rats as a Neurodevelopmental Model for Schizophrenia.
Gaskin PL, Toledo-Rodriguez M, Alexander SP, Fone KC. Gaskin PL, et al. Int J Neuropsychopharmacol. 2016 Dec 3;19(11):pyw062. doi: 10.1093/ijnp/pyw062. Print 2016 Nov. Int J Neuropsychopharmacol. 2016. PMID: 27382048 Free PMC article.