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KRAS4A directly regulates hexokinase 1.
Amendola CR, Mahaffey JP, Parker SJ, Ahearn IM, Chen WC, Zhou M, Court H, Shi J, Mendoza SL, Morten MJ, Rothenberg E, Gottlieb E, Wadghiri YZ, Possemato R, Hubbard SR, Balmain A, Kimmelman AC, Philips MR. Amendola CR, et al. Among authors: philips mr. Nature. 2019 Dec;576(7787):482-486. doi: 10.1038/s41586-019-1832-9. Epub 2019 Dec 11. Nature. 2019. PMID: 31827279 Free PMC article.
The G protein-coupled receptor GPR31 promotes membrane association of KRAS.
Fehrenbacher N, Tojal da Silva I, Ramirez C, Zhou Y, Cho KJ, Kuchay S, Shi J, Thomas S, Pagano M, Hancock JF, Bar-Sagi D, Philips MR. Fehrenbacher N, et al. Among authors: philips mr. J Cell Biol. 2017 Aug 7;216(8):2329-2338. doi: 10.1083/jcb.201609096. Epub 2017 Jun 15. J Cell Biol. 2017. PMID: 28619714 Free PMC article.
Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.
Waters AM, Ozkan-Dagliyan I, Vaseva AV, Fer N, Strathern LA, Hobbs GA, Tessier-Cloutier B, Gillette WK, Bagni R, Whiteley GR, Hartley JL, McCormick F, Cox AD, Houghton PJ, Huntsman DG, Philips MR, Der CJ. Waters AM, et al. Among authors: philips mr. Sci Signal. 2017 Sep 26;10(498):eaao3332. doi: 10.1126/scisignal.aao3332. Sci Signal. 2017. PMID: 28951536 Free PMC article.
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1 mutant lung cancer.
Deng J, Thennavan A, Dolgalev I, Chen T, Li J, Marzio A, Poirier JT, Peng DH, Bulatovic M, Mukhopadhyay S, Silver H, Papadopoulos E, Pyon V, Thakurdin C, Han H, Li F, Li S, Ding H, Hu H, Pan Y, Weerasekara V, Jiang B, Wang ES, Ahearn I, Philips M, Papagiannakopoulos T, Tsirigos A, Rothenberg E, Gainor J, Freeman GJ, Rudin CM, Gray NS, Hammerman PS, Pagano M, Heymach JV, Perou CM, Bardeesy N, Wong KK. Deng J, et al. Among authors: philips m. Nat Cancer. 2021 May;2(5):503-514. doi: 10.1038/s43018-021-00208-6. Epub 2021 May 17. Nat Cancer. 2021. PMID: 34142094 Free PMC article. No abstract available.
Ras signalling on the endoplasmic reticulum and the Golgi.
Chiu VK, Bivona T, Hach A, Sajous JB, Silletti J, Wiener H, Johnson RL 2nd, Cox AD, Philips MR. Chiu VK, et al. Nat Cell Biol. 2002 May;4(5):343-50. doi: 10.1038/ncb783. Nat Cell Biol. 2002. PMID: 11988737
FKBP12 binds to acylated H-ras and promotes depalmitoylation.
Ahearn IM, Tsai FD, Court H, Zhou M, Jennings BC, Ahmed M, Fehrenbacher N, Linder ME, Philips MR. Ahearn IM, et al. Among authors: philips mr. Mol Cell. 2011 Jan 21;41(2):173-85. doi: 10.1016/j.molcel.2011.01.001. Mol Cell. 2011. PMID: 21255728 Free PMC article.
330 results