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Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: obier n. Nat Cell Biol. 2021 Jul;23(7):704-717. doi: 10.1038/s41556-021-00707-9. Epub 2021 Jul 12. Nat Cell Biol. 2021. PMID: 34253898 Free PMC article.
Publisher Correction: Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration.
Clapes T, Polyzou A, Prater P, Sagar, Morales-Hernández A, Ferrarini MG, Kehrer N, Lefkopoulos S, Bergo V, Hummel B, Obier N, Maticzka D, Bridgeman A, Herman JS, Ilik I, Klaeylé L, Rehwinkel J, McKinney-Freeman S, Backofen R, Akhtar A, Cabezas-Wallscheid N, Sawarkar R, Rebollo R, Grün D, Trompouki E. Clapes T, et al. Among authors: obier n. Nat Cell Biol. 2021 Dec;23(12):1338. doi: 10.1038/s41556-021-00785-9. Nat Cell Biol. 2021. PMID: 34611323 Free PMC article. No abstract available.
Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity.
Schönberger K, Obier N, Romero-Mulero MC, Cauchy P, Mess J, Pavlovich PV, Zhang YW, Mitterer M, Rettkowski J, Lalioti ME, Jäcklein K, Curtis JD, Féret B, Sommerkamp P, Morganti C, Ito K, Ghyselinck NB, Trompouki E, Buescher JM, Pearce EL, Cabezas-Wallscheid N. Schönberger K, et al. Among authors: obier n. Cell Stem Cell. 2022 Jan 6;29(1):131-148.e10. doi: 10.1016/j.stem.2021.10.002. Epub 2021 Oct 26. Cell Stem Cell. 2022. PMID: 34706256 Free PMC article.
Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells.
Zhang YW, Mess J, Aizarani N, Mishra P, Johnson C, Romero-Mulero MC, Rettkowski J, Schönberger K, Obier N, Jäcklein K, Woessner NM, Lalioti ME, Velasco-Hernandez T, Sikora K, Wäsch R, Lehnertz B, Sauvageau G, Manke T, Menendez P, Walter SG, Minguet S, Laurenti E, Günther S, Grün D, Cabezas-Wallscheid N. Zhang YW, et al. Among authors: obier n. Nat Cell Biol. 2022 Jul;24(7):1038-1048. doi: 10.1038/s41556-022-00931-x. Epub 2022 Jun 20. Nat Cell Biol. 2022. PMID: 35725769 Free PMC article.
TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages.
Schuster EM, Epple MW, Glaser KM, Mihlan M, Lucht K, Zimmermann JA, Bremser A, Polyzou A, Obier N, Cabezas-Wallscheid N, Trompouki E, Ballabio A, Vogel J, Buescher JM, Westermann AJ, Rambold AS. Schuster EM, et al. Among authors: obier n. Nat Metab. 2022 Jul;4(7):856-866. doi: 10.1038/s42255-022-00605-w. Epub 2022 Jul 21. Nat Metab. 2022. PMID: 35864246 Free PMC article.
Transcriptional reprogramming by mutated IRF4 in lymphoma.
Schleussner N, Cauchy P, Franke V, Giefing M, Fornes O, Vankadari N, Assi SA, Costanza M, Weniger MA, Akalin A, Anagnostopoulos I, Bukur T, Casarotto MG, Damm F, Daumke O, Edginton-White B, Gebhardt JCM, Grau M, Grunwald S, Hansmann ML, Hartmann S, Huber L, Kärgel E, Lusatis S, Noerenberg D, Obier N, Pannicke U, Fischer A, Reisser A, Rosenwald A, Schwarz K, Sundararaj S, Weilemann A, Winkler W, Xu W, Lenz G, Rajewsky K, Wasserman WW, Cockerill PN, Scheidereit C, Siebert R, Küppers R, Grosschedl R, Janz M, Bonifer C, Mathas S. Schleussner N, et al. Among authors: obier n. Nat Commun. 2023 Nov 7;14(1):6947. doi: 10.1038/s41467-023-41954-8. Nat Commun. 2023. PMID: 37935654 Free PMC article.
Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.
Goode DK, Obier N, Vijayabaskar MS, Lie-A-Ling M, Lilly AJ, Hannah R, Lichtinger M, Batta K, Florkowska M, Patel R, Challinor M, Wallace K, Gilmour J, Assi SA, Cauchy P, Hoogenkamp M, Westhead DR, Lacaud G, Kouskoff V, Göttgens B, Bonifer C. Goode DK, et al. Among authors: obier n. Dev Cell. 2016 Mar 7;36(5):572-87. doi: 10.1016/j.devcel.2016.01.024. Epub 2016 Feb 25. Dev Cell. 2016. PMID: 26923725 Free PMC article.
Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets.
Vijayabaskar MS, Goode DK, Obier N, Lichtinger M, Emmett AML, Abidin FNZ, Shar N, Hannah R, Assi SA, Lie-A-Ling M, Gottgens B, Lacaud G, Kouskoff V, Bonifer C, Westhead DR. Vijayabaskar MS, et al. Among authors: obier n. PLoS Comput Biol. 2019 Nov 4;15(11):e1007337. doi: 10.1371/journal.pcbi.1007337. eCollection 2019 Nov. PLoS Comput Biol. 2019. PMID: 31682597 Free PMC article.
32 results