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Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine.
Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, Poral AH, Tran T, Georgiou DK, Arthur K, Lin YH, Satani N, Ballato ES, Behr EI, deCarvalho AC, Verhaak RGW, de Groot J, Huse JT, Asara JM, Kalluri R, Muller FL. Barekatain Y, et al. Among authors: wang l. Nat Commun. 2021 Jul 9;12(1):4228. doi: 10.1038/s41467-021-24240-3. Nat Commun. 2021. PMID: 34244484 Free PMC article.
A genetic model of methionine restriction extends Drosophila health- and lifespan.
Parkhitko AA, Wang L, Filine E, Jouandin P, Leshchiner D, Binari R, Asara JM, Rabinowitz JD, Perrimon N. Parkhitko AA, et al. Among authors: wang l. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2110387118. doi: 10.1073/pnas.2110387118. Proc Natl Acad Sci U S A. 2021. PMID: 34588310 Free PMC article.
Slow TCA flux and ATP production in primary solid tumours but not metastases.
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD. Bartman CR, et al. Among authors: wang l. Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1. Nature. 2023. PMID: 36725930 Free PMC article.
SLC25A51 is a mammalian mitochondrial NAD+ transporter.
Luongo TS, Eller JM, Lu MJ, Niere M, Raith F, Perry C, Bornstein MR, Oliphint P, Wang L, McReynolds MR, Migaud ME, Rabinowitz JD, Johnson FB, Johnsson K, Ziegler M, Cambronne XA, Baur JA. Luongo TS, et al. Among authors: wang l. Nature. 2020 Dec;588(7836):174-179. doi: 10.1038/s41586-020-2741-7. Epub 2020 Sep 9. Nature. 2020. PMID: 32906142 Free PMC article.
Metabolite discovery through global annotation of untargeted metabolomics data.
Chen L, Lu W, Wang L, Xing X, Chen Z, Teng X, Zeng X, Muscarella AD, Shen Y, Cowan A, McReynolds MR, Kennedy BJ, Lato AM, Campagna SR, Singh M, Rabinowitz JD. Chen L, et al. Among authors: wang l. Nat Methods. 2021 Nov;18(11):1377-1385. doi: 10.1038/s41592-021-01303-3. Epub 2021 Oct 28. Nat Methods. 2021. PMID: 34711973 Free PMC article.
Methionine synthase supports tumour tetrahydrofolate pools.
Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD. Ghergurovich JM, et al. Among authors: wang jz, wang l. Nat Metab. 2021 Nov;3(11):1512-1520. doi: 10.1038/s42255-021-00465-w. Epub 2021 Nov 18. Nat Metab. 2021. PMID: 34799699 Free PMC article.
Spatially resolved isotope tracing reveals tissue metabolic activity.
Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD, Davidson SM. Wang L, et al. Nat Methods. 2022 Feb;19(2):223-230. doi: 10.1038/s41592-021-01378-y. Epub 2022 Feb 7. Nat Methods. 2022. PMID: 35132243 Free PMC article.
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