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First-in-Human Phase I Study of ABBV-085, an Antibody-Drug Conjugate Targeting LRRC15, in Sarcomas and Other Advanced Solid Tumors.
Demetri GD, Luke JJ, Hollebecque A, Powderly JD 2nd, Spira AI, Subbiah V, Naumovski L, Chen C, Fang H, Lai DW, Yue H, Polepally AR, Purcell JW, Robinson R, Sharma P, Allison JP, Tolcher A, Villalobos VM. Demetri GD, et al. Among authors: chen c. Clin Cancer Res. 2021 Jul 1;27(13):3556-3566. doi: 10.1158/1078-0432.CCR-20-4513. Epub 2021 Apr 5. Clin Cancer Res. 2021. PMID: 33820780 Clinical Trial.
A phase 1 study of the pan-bromodomain and extraterminal inhibitor mivebresib (ABBV-075) alone or in combination with venetoclax in patients with relapsed/refractory acute myeloid leukemia.
Borthakur G, Odenike O, Aldoss I, Rizzieri DA, Prebet T, Chen C, Popovic R, Modi DA, Joshi RH, Wolff JE, Jonas BA. Borthakur G, et al. Among authors: chen c. Cancer. 2021 Aug 15;127(16):2943-2953. doi: 10.1002/cncr.33590. Epub 2021 May 2. Cancer. 2021. PMID: 33934351 Free PMC article. Clinical Trial.
The therapeutically actionable long non-coding RNA 'T-RECS' is essential to cancer cells' survival in NRAS/MAPK-driven melanoma.
Feichtenschlager V, Chen L, Zheng YJ, Ho W, Sanlorenzo M, Vujic I, Fewings E, Lee A, Chen C, Callanan C, Lin K, Qu T, Hohlova D, Vujic M, Hwang Y, Lai K, Chen S, Nguyen T, Muñoz DP, Kohwi Y, Posch C, Daud A, Rappersberger K, Kohwi-Shigematsu T, Coppé JP, Ortiz-Urda S. Feichtenschlager V, et al. Among authors: chen l, chen c, chen s. Mol Cancer. 2024 Feb 22;23(1):40. doi: 10.1186/s12943-024-01955-7. Mol Cancer. 2024. PMID: 38383439 Free PMC article.
Correlation between night sweats and season fluctuation in China.
Chen C, Li M, Peng F, Lv D, Ding X, Tian C, Ren W, Meng X, Sun T, Wang Y, Du H, Wu F, Li W, Wang P. Chen C, et al. Front Public Health. 2025 Jan 9;12:1423698. doi: 10.3389/fpubh.2024.1423698. eCollection 2024. Front Public Health. 2025. PMID: 39850865 Free PMC article.
Effect of astragalus membranaceus on neurological function in acute aneurysmal subarachnoid hemorrhage patients with high inflammation: A preliminary randomized, double-blind, placebo-controlled clinical trial.
Chen CC, Lin HL, Guo JH, Chen X, Cho DY, Liao WL, Hsieh CL. Chen CC, et al. J Tradit Complement Med. 2024 Apr 11;14(6):635-643. doi: 10.1016/j.jtcme.2024.04.002. eCollection 2024 Nov. J Tradit Complement Med. 2024. PMID: 39850599 Free PMC article.
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