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Page 1
Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. Lau RK, et al. Among authors: mathews it. Mol Cell. 2020 Feb 20;77(4):723-733.e6. doi: 10.1016/j.molcel.2019.12.010. Epub 2020 Jan 10. Mol Cell. 2020. PMID: 31932164 Free PMC article.
CBASS Immunity Uses CARF-Related Effectors to Sense 3'-5'- and 2'-5'-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection.
Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, Kranzusch PJ. Lowey B, et al. Among authors: mathews it. Cell. 2020 Jul 9;182(1):38-49.e17. doi: 10.1016/j.cell.2020.05.019. Epub 2020 Jun 15. Cell. 2020. PMID: 32544385 Free PMC article.
Cellular sensing of extracellular purine nucleosides triggers an innate IFN-β response.
Dhanwani R, Takahashi M, Mathews IT, Lenzi C, Romanov A, Watrous JD, Pieters B, Hedrick CC, Benedict CA, Linden J, Nilsson R, Jain M, Sharma S. Dhanwani R, et al. Among authors: mathews it. Sci Adv. 2020 Jul 22;6(30):eaba3688. doi: 10.1126/sciadv.aba3688. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32743071 Free PMC article.
Functional Analysis of Immune Signature Genes in Th1* Memory Cells Links ISOC1 and Pyrimidine Metabolism to IFN-γ and IL-17 Production.
Kushnareva Y, Mathews IT, Andreyev AY, Altay G, Lindestam Arlehamn CS, Pandurangan V, Nilsson R, Jain M, Sette A, Peters B, Sharma S. Kushnareva Y, et al. Among authors: mathews it. J Immunol. 2021 Mar 15;206(6):1181-1193. doi: 10.4049/jimmunol.2000672. Epub 2021 Feb 5. J Immunol. 2021. PMID: 33547171 Free PMC article.
Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease.
Chu X, Jaeger M, Beumer J, Bakker OB, Aguirre-Gamboa R, Oosting M, Smeekens SP, Moorlag S, Mourits VP, Koeken VACM, de Bree C, Jansen T, Mathews IT, Dao K, Najhawan M, Watrous JD, Joosten I, Sharma S, Koenen HJPM, Withoff S, Jonkers IH, Netea-Maier RT, Xavier RJ, Franke L, Xu CJ, Joosten LAB, Sanna S, Jain M, Kumar V, Clevers H, Wijmenga C, Netea MG, Li Y. Chu X, et al. Among authors: mathews it. Genome Biol. 2021 Jul 6;22(1):198. doi: 10.1186/s13059-021-02413-z. Genome Biol. 2021. PMID: 34229738 Free PMC article.
Metabolic programs of T cell tissue residency empower tumour immunity.
Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, Sharma S, Krummel MF, Chi H, Bensinger SJ, Goldrath AW. Reina-Campos M, et al. Among authors: mathews it. Nature. 2023 Sep;621(7977):179-187. doi: 10.1038/s41586-023-06483-w. Epub 2023 Aug 30. Nature. 2023. PMID: 37648857 Free PMC article.
Linoleoyl-lysophosphatidylcholine suppresses immune-related adverse events due to immune checkpoint blockade.
Mathews IT, Saminathan P, Henglin M, Liu M, Nadig N, Fang C, Mercader K, Chee SJ, Campbell AM, Patel AA, Tiwari S, Watrous JD, Ramesh K, Dicker M, Dao K, Meyer MA, Jousilahti P, Havulinna AS, Niiranen T, Salomaa V, Joosten LAB, Netea MG, Zheng P, Kronenberg M, Patel SP, Gutkind JS, Ottensmeier C, Long T, Kaech SM, Hedrick CC, Cheng S, Jain M, Sharma S. Mathews IT, et al. medRxiv [Preprint]. 2024 Aug 8:2024.08.07.24310974. doi: 10.1101/2024.08.07.24310974. medRxiv. 2024. PMID: 39148854 Free PMC article. Preprint.
ReIGNITE Radiation Therapy Boost: A Prospective, International Study of Radiation Oncologists' Accuracy in Contouring Prostate Tumors for Focal Radiation Therapy Boost on Conventional Magnetic Resonance Imaging Alone or With Assistance of Restriction Spectrum Imaging.
Lui AJ, Kallis K, Zhong AY, Hussain TS, Conlin C, Digma LA, Phan N, Mathews IT, Do DD, Domingo MR, Karunamuni R, Kuperman J, Dale AM, Shabaik A, Rakow-Penner R, Hahn ME, Seibert TM. Lui AJ, et al. Among authors: mathews it. Int J Radiat Oncol Biol Phys. 2023 Dec 1;117(5):1145-1152. doi: 10.1016/j.ijrobp.2023.07.004. Epub 2023 Jul 14. Int J Radiat Oncol Biol Phys. 2023. PMID: 37453559 Free PMC article.
15 results