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Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs.
Xu L, Chen B, Schihada H, Wright SC, Turku A, Wu Y, Han GW, Kowalski-Jahn M, Kozielewicz P, Bowin CF, Zhang X, Li C, Bouvier M, Schulte G, Xu F. Xu L, et al. Among authors: wright sc. Cell Res. 2021 Dec;31(12):1311-1314. doi: 10.1038/s41422-021-00525-6. Epub 2021 Jul 8. Cell Res. 2021. PMID: 34239071 Free PMC article. No abstract available.
Frizzleds as GPCRs - More Conventional Than We Thought!
Schulte G, Wright SC. Schulte G, et al. Among authors: wright sc. Trends Pharmacol Sci. 2018 Sep;39(9):828-842. doi: 10.1016/j.tips.2018.07.001. Epub 2018 Jul 23. Trends Pharmacol Sci. 2018. PMID: 30049420 Review.
Agonist-induced formation of unproductive receptor-G12 complexes.
Okashah N, Wright SC, Kawakami K, Mathiasen S, Zhou J, Lu S, Javitch JA, Inoue A, Bouvier M, Lambert NA. Okashah N, et al. Among authors: wright sc. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21723-21730. doi: 10.1073/pnas.2003787117. Epub 2020 Aug 17. Proc Natl Acad Sci U S A. 2020. PMID: 32817560 Free PMC article.
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz É, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM. Wright SC, et al. Nat Commun. 2023 Oct 9;14(1):6243. doi: 10.1038/s41467-023-41893-4. Nat Commun. 2023. PMID: 37813859 Free PMC article.
179 results