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Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
Gebert J, Gelincik O, Oezcan-Wahlbrink M, Marshall JD, Hernandez-Sanchez A, Urban K, Long M, Cortes E, Tosti E, Katzenmaier EM, Song Y, Elsaadi A, Deng N, Vilar E, Fuchs V, Nelius N, Yuan YP, Ahadova A, Sei S, Shoemaker RH, Umar A, Wei L, Liu S, Bork P, Edelmann W, von Knebel Doeberitz M, Lipkin SM, Kloor M. Gebert J, et al. Among authors: vilar e. Gastroenterology. 2021 Oct;161(4):1288-1302.e13. doi: 10.1053/j.gastro.2021.06.073. Epub 2021 Jul 2. Gastroenterology. 2021. PMID: 34224739 Free PMC article.
Cancer Moonshot Immuno-Oncology Translational Network (IOTN): accelerating the clinical translation of basic discoveries for improving immunotherapy and immunoprevention of cancer.
Annapragada A, Sikora A, Bollard C, Conejo-Garcia J, Cruz CR, Demehri S, Demetriou M, Demirdjian L, Fong L, Horowitz M, Hutson A, Kadash-Edmondson K, Kufe D, Lipkin S, Liu S, McCarthy C, Morgan M, Morris Z, Pan Y, Pasquini M, Schoenberger S, Van Allen E, Vilar E, Xing Y, Zha W; IOTN Consortium; Odunsi A. Annapragada A, et al. Among authors: vilar e. J Immunother Cancer. 2020 Jun;8(1):e000796. doi: 10.1136/jitc-2020-000796. J Immunother Cancer. 2020. PMID: 32554617 Free PMC article. Review.
Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa.
Reyes-Uribe L, Wu W, Gelincik O, Bommi PV, Francisco-Cruz A, Solis LM, Lynch PM, Lim R, Stoffel EM, Kanth P, Samadder NJ, Mork ME, Taggart MW, Milne GL, Marnett LJ, Vornik L, Liu DD, Revuelta M, Chang K, You YN, Kopelovich L, Wistuba II, Lee JJ, Sei S, Shoemaker RH, Szabo E, Richmond E, Umar A, Perloff M, Brown PH, Lipkin SM, Vilar E. Reyes-Uribe L, et al. Among authors: vilar e. Gut. 2021 Mar;70(3):555-566. doi: 10.1136/gutjnl-2020-320946. Epub 2020 Jul 8. Gut. 2021. PMID: 32641470 Free PMC article. Clinical Trial.
The Transcriptomic Landscape of Mismatch Repair-Deficient Intestinal Stem Cells.
Bommi PV, Bowen CM, Reyes-Uribe L, Wu W, Katayama H, Rocha P, Parra ER, Francisco-Cruz A, Ozcan Z, Tosti E, Willis JA, Wu H, Taggart MW, Burks JK, Lynch PM, Edelmann W, Scheet PA, Wistuba II, Sinha KM, Hanash SM, Vilar E. Bommi PV, et al. Among authors: vilar e. Cancer Res. 2021 May 15;81(10):2760-2773. doi: 10.1158/0008-5472.CAN-20-2896. Epub 2021 Mar 18. Cancer Res. 2021. PMID: 34003775 Free PMC article.
250 results