Suzuki T - Search Results

1

Identification of Novel Histone Deacetylase 6-Selective Inhibitors Bearing 3,3,3-Trifluorolactic Amide (TFLAM) Motif as a Zinc Binding Group.

Kurohara T, Tanaka K, Takahashi D, Ueda S, Yamashita Y, Takada Y, Takeshima H, Yu S, Itoh Y, Hase K, Suzuki T. Kurohara T, et al. Among authors: suzuki t. Chembiochem. 2021 Nov 16;22(22):3158-3163. doi: 10.1002/cbic.202100255. Epub 2021 Jul 9. Chembiochem. 2021. PMID: 34224197

2

Highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate.

Suzuki T, Kouketsu A, Itoh Y, Hisakawa S, Maeda S, Yoshida M, Nakagawa H, Miyata N. Suzuki T, et al. J Med Chem. 2006 Aug 10;49(16):4809-12. doi: 10.1021/jm060554y. J Med Chem. 2006. PMID: 16884291

3

Identification of a potent and stable antiproliferative agent by the prodrug formation of a thiolate histone deacetylase inhibitor.

Suzuki T, Hisakawa S, Itoh Y, Maruyama S, Kurotaki M, Nakagawa H, Miyata N. Suzuki T, et al. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1558-61. doi: 10.1016/j.bmcl.2006.12.117. Epub 2007 Jan 13. Bioorg Med Chem Lett. 2007. PMID: 17257837

4

Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors.

Suzuki T, Hisakawa S, Itoh Y, Suzuki N, Takahashi K, Kawahata M, Yamaguchi K, Nakagawa H, Miyata N. Suzuki T, et al. Among authors: suzuki n. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4208-12. doi: 10.1016/j.bmcl.2007.05.040. Epub 2007 May 17. Bioorg Med Chem Lett. 2007. PMID: 17532630

5

Design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors.

Itoh Y, Suzuki T, Kouketsu A, Suzuki N, Maeda S, Yoshida M, Nakagawa H, Miyata N. Itoh Y, et al. Among authors: suzuki n, suzuki t. J Med Chem. 2007 Nov 1;50(22):5425-38. doi: 10.1021/jm7009217. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929798

6

Isoform-selective histone deacetylase inhibitors.

Itoh Y, Suzuki T, Miyata N. Itoh Y, et al. Among authors: suzuki t. Curr Pharm Des. 2008;14(6):529-44. doi: 10.2174/138161208783885335. Curr Pharm Des. 2008. PMID: 18336298 Review.

7

Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.

Hamada S, Kim TD, Suzuki T, Itoh Y, Tsumoto H, Nakagawa H, Janknecht R, Miyata N. Hamada S, et al. Among authors: suzuki t. Bioorg Med Chem Lett. 2009 May 15;19(10):2852-5. doi: 10.1016/j.bmcl.2009.03.098. Epub 2009 Mar 26. Bioorg Med Chem Lett. 2009. PMID: 19359167

8

Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.

Hamada S, Suzuki T, Mino K, Koseki K, Oehme F, Flamme I, Ozasa H, Itoh Y, Ogasawara D, Komaarashi H, Kato A, Tsumoto H, Nakagawa H, Hasegawa M, Sasaki R, Mizukami T, Miyata N. Hamada S, et al. Among authors: suzuki t. J Med Chem. 2010 Aug 12;53(15):5629-38. doi: 10.1021/jm1003655. J Med Chem. 2010. PMID: 20684604

9

Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors.

Suzuki T, Khan MN, Sawada H, Imai E, Itoh Y, Yamatsuta K, Tokuda N, Takeuchi J, Seko T, Nakagawa H, Miyata N. Suzuki T, et al. J Med Chem. 2012 Jun 28;55(12):5760-73. doi: 10.1021/jm3002108. Epub 2012 Jun 12. J Med Chem. 2012. PMID: 22642300

10

Rapid discovery of highly potent and selective inhibitors of histone deacetylase 8 using click chemistry to generate candidate libraries.

Suzuki T, Ota Y, Ri M, Bando M, Gotoh A, Itoh Y, Tsumoto H, Tatum PR, Mizukami T, Nakagawa H, Iida S, Ueda R, Shirahige K, Miyata N. Suzuki T, et al. J Med Chem. 2012 Nov 26;55(22):9562-75. doi: 10.1021/jm300837y. Epub 2012 Nov 12. J Med Chem. 2012. PMID: 23116147

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