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Page 1
Methylprednisolone Pulses Plus Tacrolimus in Addition to Standard of Care vs. Standard of Care Alone in Patients With Severe COVID-19. A Randomized Controlled Trial.
Solanich X, Antolí A, Rocamora-Blanch G, Padullés N, Fanlo-Maresma M, Iriarte A, Mitjavila F, Capdevila O, Riera-Mestre A, Bas J, Vicens-Zygmunt V, Niubó J, Calvo N, Bolivar S, Rigo-Bonnin R, Mensa-Vilaró A, Arregui L, Tebe C, Videla S, Hereu P, Corbella X. Solanich X, et al. Among authors: antoli a. Front Med (Lausanne). 2021 Jun 14;8:691712. doi: 10.3389/fmed.2021.691712. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34195214 Free PMC article.
Beneficial effect of corticosteroids in preventing mortality in patients receiving tocilizumab to treat severe COVID-19 illness.
Rubio-Rivas M, Ronda M, Padulles A, Mitjavila F, Riera-Mestre A, García-Forero C, Iriarte A, Mora JM, Padulles N, Gonzalez M, Solanich X, Gasa M, Suarez-Cuartin G, Sabater J, Perez-Fernandez XL, Santacana E, Leiva E, Ariza-Sole A, Dallaglio PD, Quero M, Soriano A, Pasqualetto A, Koo M, Esteve V, Antoli A, Moreno-Gonzalez R, Yun S, Cerda P, Llaberia M, Formiga F, Fanlo M, Montero A, Chivite D, Capdevila O, Bolao F, Pinto X, Llop J, Sabate A, Guardiola J, Cruzado JM, Comin-Colet J, Santos S, Jodar R, Corbella X. Rubio-Rivas M, et al. Among authors: antoli a. Int J Infect Dis. 2020 Dec;101:290-297. doi: 10.1016/j.ijid.2020.09.1486. Epub 2020 Oct 6. Int J Infect Dis. 2020. PMID: 33035673 Free PMC article.
Pragmatic, open-label, single-center, randomized, phase II clinical trial to evaluate the efficacy and safety of methylprednisolone pulses and tacrolimus in patients with severe pneumonia secondary to COVID-19: The TACROVID trial protocol.
Solanich X, Antolí A, Padullés N, Fanlo-Maresma M, Iriarte A, Mitjavila F, Capdevila O, Molina M, Sabater J, Bas J, Mensa-Vilaró A, Niubó J, Calvo N, Bolivar S, Rigo-Bonnin R, Arregui L, Tebé C, Hereu P, Videla S, Corbella X. Solanich X, et al. Among authors: antoli a. Contemp Clin Trials Commun. 2021 Mar;21:100716. doi: 10.1016/j.conctc.2021.100716. Epub 2021 Jan 19. Contemp Clin Trials Commun. 2021. PMID: 33495742 Free PMC article. Review.
Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19.
Solanich X, Vargas-Parra G, van der Made CI, Simons A, Schuurs-Hoeijmakers J, Antolí A, Del Valle J, Rocamora-Blanch G, Setién F, Esteller M, van Reijmersdal SV, Riera-Mestre A, Sabater-Riera J, Capellá G, van de Veerdonk FL, van der Hoven B, Corbella X, Hoischen A, Lázaro C. Solanich X, et al. Among authors: antoli a. Front Immunol. 2021 Jul 23;12:719115. doi: 10.3389/fimmu.2021.719115. eCollection 2021. Front Immunol. 2021. PMID: 34367187 Free PMC article. Clinical Trial.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Pre-existing Autoantibodies Neutralizing High Concentrations of Type I Interferons in Almost 10% of COVID-19 Patients Admitted to Intensive Care in Barcelona.
Solanich X, Rigo-Bonnin R, Gumucio VD, Bastard P, Rosain J, Philippot Q, Perez-Fernandez XL, Fuset-Cabanes MP, Gordillo-Benitez MÁ, Suarez-Cuartin G, Boza-Hernandez E, Riera-Mestre A, Parra-Martínez A, Colobran R, Antolí A, Navarro S, Rocamora-Blanch G, Framil M, Calatayud L, Corbella X, Casanova JL, Morandeira F, Sabater-Riera J. Solanich X, et al. Among authors: antoli a. J Clin Immunol. 2021 Nov;41(8):1733-1744. doi: 10.1007/s10875-021-01136-x. Epub 2021 Sep 27. J Clin Immunol. 2021. PMID: 34570326 Free PMC article.
A multicenter, open-label, randomized, proof-of-concept phase II clinical trial to assess the efficacy and safety of icatibant in patients infected with SARS-CoV-2 (COVID-19) and admitted to hospital units without invasive mechanical ventilation: study protocol (ICAT-COVID).
Malchair P, Otero A, Giol J, Solanich X, Carnaval T, Fernández-Nistal A, Sánchez-Gabriel A, Montoto C, Lleonart R, Videla S; ICAT-COVID team. Malchair P, et al. Trials. 2022 Apr 12;23(1):303. doi: 10.1186/s13063-022-06219-7. Trials. 2022. PMID: 35413921 Free PMC article.
Evaluation of Humoral and Cellular Immune Responses to the SARS-CoV-2 Vaccine in Patients With Common Variable Immunodeficiency Phenotype and Patient Receiving B-Cell Depletion Therapy.
Antolí A, Rocamora-Blanch G, Framil M, Mas-Bosch V, Navarro S, Bermudez C, Martinez-Yelamos S, Dopico E, Calatayud L, Garcia-Muñoz N, Hernández-Benítez LH, Riera-Mestre A, Bas J, Masuet-Aumatell C, Rigo-Bonnin R, Morandeira F, Solanich X. Antolí A, et al. Front Immunol. 2022 Apr 29;13:895209. doi: 10.3389/fimmu.2022.895209. eCollection 2022. Front Immunol. 2022. PMID: 35572562 Free PMC article.
30 results