Sylvester K - Search Results

1

Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts.

Sylvester K, Maher SP, Posfai D, Tran MK, Crawford MC, Vantaux A, Witkowski B, Kyle DE, Derbyshire ER. Sylvester K, et al. Front Cell Infect Microbiol. 2021 Jun 14;11:687019. doi: 10.3389/fcimb.2021.687019. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34195101 Free PMC article.

2

Plasmodium parasite exploits host aquaporin-3 during liver stage malaria infection.

Posfai D, Sylvester K, Reddy A, Ganley JG, Wirth J, Cullen QE, Dave T, Kato N, Dave SS, Derbyshire ER. Posfai D, et al. Among authors: sylvester k. PLoS Pathog. 2018 May 18;14(5):e1007057. doi: 10.1371/journal.ppat.1007057. eCollection 2018 May. PLoS Pathog. 2018. PMID: 29775485 Free PMC article.

3

In silico Screening and Evaluation of Plasmodium falciparum Protein Kinase 5 (PK5) Inhibitors.

Eubanks AL, Perkins MM, Sylvester K, Ganley JG, Posfai D, Sanschargrin PC, Hong J, Sliz P, Derbyshire ER. Eubanks AL, et al. Among authors: sylvester k. ChemMedChem. 2018 Dec 6;13(23):2479-2483. doi: 10.1002/cmdc.201800625. Epub 2018 Nov 8. ChemMedChem. 2018. PMID: 30328274 Free PMC article.

4

Synthesis and Analysis of Natural-Product-Like Macrocycles by Tandem Oxidation/Oxa-Conjugate Addition Reactions.

Lee H, Sylvester K, Derbyshire ER, Hong J. Lee H, et al. Among authors: sylvester k. Chemistry. 2019 May 7;25(26):6500-6504. doi: 10.1002/chem.201900620. Epub 2019 Apr 17. Chemistry. 2019. PMID: 30912197

5

Close the ring to break the cycle: tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo[1,2-a]quinolin-5-ones with potent anti-protozoal activity.

Szamosvári D , Sylvester K , Schmid P , Lu KY , Derbyshire ER , Böttcher T . Szamosvári D , et al. Among authors: sylvester k. Chem Commun (Camb). 2019 Jun 13;55(49):7009-7012. doi: 10.1039/c9cc01689a. Chem Commun (Camb). 2019. PMID: 31119221 Free PMC article.

6

RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection.

Toro-Moreno M, Sylvester K, Srivastava T, Posfai D, Derbyshire ER. Toro-Moreno M, et al. Among authors: sylvester k. mBio. 2020 Feb 4;11(1):e03234-19. doi: 10.1128/mBio.03234-19. mBio. 2020. PMID: 32019802 Free PMC article.

7

Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy.

Lu KY, Quan B, Sylvester K, Srivastava T, Fitzgerald MC, Derbyshire ER. Lu KY, et al. Among authors: sylvester k. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):5810-5817. doi: 10.1073/pnas.1913525117. Epub 2020 Mar 3. Proc Natl Acad Sci U S A. 2020. PMID: 32127489 Free PMC article.

8

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3.

Posfai D, Maher SP, Roesch C, Vantaux A, Sylvester K, Péneau J, Popovici J, Kyle DE, Witkowski B, Derbyshire ER. Posfai D, et al. Among authors: sylvester k. Cell Chem Biol. 2020 Jun 18;27(6):719-727.e5. doi: 10.1016/j.chembiol.2020.03.009. Epub 2020 Apr 23. Cell Chem Biol. 2020. PMID: 32330444 Free PMC article.

9

A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity.

Ganley JG, Pandey A, Sylvester K, Lu KY, Toro-Moreno M, Rütschlin S, Bradford JM, Champion CJ, Böttcher T, Xu J, Derbyshire ER. Ganley JG, et al. Among authors: sylvester k. Cell Chem Biol. 2020 Jul 16;27(7):817-826.e5. doi: 10.1016/j.chembiol.2020.06.004. Epub 2020 Jul 2. Cell Chem Biol. 2020. PMID: 32619453 Free article.

10

Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance.

Tye MA, Payne NC, Johansson C, Singh K, Santos SA, Fagbami L, Pant A, Sylvester K, Luth MR, Marques S, Whitman M, Mota MM, Winzeler EA, Lukens AK, Derbyshire ER, Oppermann U, Wirth DF, Mazitschek R. Tye MA, et al. Among authors: sylvester k. Nat Commun. 2022 Aug 25;13(1):4976. doi: 10.1038/s41467-022-32630-4. Nat Commun. 2022. PMID: 36008486 Free PMC article.

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