Rutherford TJ - Search Results

1

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.

Gattkowski E, Rutherford TJ, Möckl F, Bauche A, Sander S, Fliegert R, Tidow H. Gattkowski E, et al. Among authors: rutherford tj. FEBS J. 2021 Dec;288(23):6769-6782. doi: 10.1111/febs.16097. Epub 2021 Jul 13. FEBS J. 2021. PMID: 34189846 Free PMC article.

2

Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2.

Gattkowski E, Johnsen A, Bauche A, Möckl F, Kulow F, Garcia Alai M, Rutherford TJ, Fliegert R, Tidow H. Gattkowski E, et al. Among authors: rutherford tj. Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1162-1170. doi: 10.1016/j.bbamcr.2018.12.010. Epub 2018 Dec 22. Biochim Biophys Acta Mol Cell Res. 2019. PMID: 30584900 Free PMC article.

3

Solution structure of ASPP2 N-terminal domain (N-ASPP2) reveals a ubiquitin-like fold.

Tidow H, Andreeva A, Rutherford TJ, Fersht AR. Tidow H, et al. Among authors: rutherford tj. J Mol Biol. 2007 Aug 24;371(4):948-58. doi: 10.1016/j.jmb.2007.05.024. Epub 2007 May 13. J Mol Biol. 2007. PMID: 17594908

4

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.

Wells M, Tidow H, Rutherford TJ, Markwick P, Jensen MR, Mylonas E, Svergun DI, Blackledge M, Fersht AR. Wells M, et al. Among authors: rutherford tj. Proc Natl Acad Sci U S A. 2008 Apr 15;105(15):5762-7. doi: 10.1073/pnas.0801353105. Epub 2008 Apr 7. Proc Natl Acad Sci U S A. 2008. PMID: 18391200 Free PMC article.

5

Solution structure of the U11-48K CHHC zinc-finger domain that specifically binds the 5' splice site of U12-type introns.

Tidow H, Andreeva A, Rutherford TJ, Fersht AR. Tidow H, et al. Among authors: rutherford tj. Structure. 2009 Feb 13;17(2):294-302. doi: 10.1016/j.str.2008.11.013. Structure. 2009. PMID: 19217400 Free article.

6

Solution structure of p53 core domain: structural basis for its instability.

Cañadillas JM, Tidow H, Freund SM, Rutherford TJ, Ang HC, Fersht AR. Cañadillas JM, et al. Among authors: rutherford tj. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2109-14. doi: 10.1073/pnas.0510941103. Epub 2006 Feb 6. Proc Natl Acad Sci U S A. 2006. PMID: 16461916 Free PMC article.

7

Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir.

Bennett MS, Wien F, Champness JN, Batuwangala T, Rutherford T, Summers WC, Sun H, Wright G, Sanderson MR. Bennett MS, et al. FEBS Lett. 1999 Jan 25;443(2):121-5. doi: 10.1016/s0014-5793(98)01619-6. FEBS Lett. 1999. PMID: 9989588 Free article.

8

Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.

Miller TC, Rutherford TJ, Johnson CM, Fiedler M, Bienz M. Miller TC, et al. Among authors: rutherford tj. J Mol Biol. 2010 Sep 3;401(5):969-84. doi: 10.1016/j.jmb.2010.07.007. Epub 2010 Jul 14. J Mol Biol. 2010. PMID: 20637214 Free PMC article.

9

Competitive binding of a benzimidazole to the histone-binding pocket of the Pygo PHD finger.

Miller TC, Rutherford TJ, Birchall K, Chugh J, Fiedler M, Bienz M. Miller TC, et al. Among authors: rutherford tj. ACS Chem Biol. 2014 Dec 19;9(12):2864-74. doi: 10.1021/cb500585s. Epub 2014 Oct 24. ACS Chem Biol. 2014. PMID: 25323450 Free PMC article.

10

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

Licchesi JD, Mieszczanek J, Mevissen TE, Rutherford TJ, Akutsu M, Virdee S, El Oualid F, Chin JW, Ovaa H, Bienz M, Komander D. Licchesi JD, et al. Among authors: rutherford tj. Nat Struct Mol Biol. 2011 Dec 11;19(1):62-71. doi: 10.1038/nsmb.2169. Nat Struct Mol Biol. 2011. PMID: 22157957 Free PMC article.

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