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Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model.
Frenkel N, Poghosyan S, Alarcón CR, García SB, Queiroz K, van den Bent L, Laoukili J, Rinkes IB, Vulto P, Kranenburg O, Hagendoorn J. Frenkel N, et al. Among authors: kranenburg o. ACS Biomater Sci Eng. 2021 Jul 12;7(7):3030-3042. doi: 10.1021/acsbiomaterials.0c01378. Epub 2021 Jun 29. ACS Biomater Sci Eng. 2021. PMID: 34185991
Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.
Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A. Matondo RB, et al. Among authors: kranenburg o. Oncotarget. 2016 Aug 23;7(34):54662-54675. doi: 10.18632/oncotarget.9952. Oncotarget. 2016. PMID: 27323406 Free PMC article.
Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability.
Jongen JMJ, van der Waals LM, Trumpi K, Laoukili J, Peters NA, Schenning-van Schelven SJ, Govaert KM, Borel Rinkes IHM, Kranenburg O. Jongen JMJ, et al. Among authors: kranenburg o. Oncotarget. 2017 Sep 21;8(49):86296-86311. doi: 10.18632/oncotarget.21145. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156796 Free PMC article.
Macrophages induce "budding" in aggressive human colon cancer subtypes by protease-mediated disruption of tight junctions.
Trumpi K, Frenkel N, Peters T, Korthagen NM, Jongen JMJ, Raats D, van Grevenstein H, Backes Y, Moons LM, Lacle MM, Koster J, Zwijnenburg D, Borel Rinkes IHM, Kranenburg O. Trumpi K, et al. Among authors: kranenburg o. Oncotarget. 2018 Apr 13;9(28):19490-19507. doi: 10.18632/oncotarget.24626. eCollection 2018 Apr 13. Oncotarget. 2018. PMID: 29731961 Free PMC article.
Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment.
van der Waals LM, Jongen JMJ, Elias SG, Veremiyenko K, Trumpi K, Trinh A, Laoukili J, Ubink I, Schenning-van Schelven SJ, van Diest PJ, Borel Rinkes IHM, Kranenburg O. van der Waals LM, et al. Among authors: kranenburg o. Am J Pathol. 2018 Oct;188(10):2369-2377. doi: 10.1016/j.ajpath.2018.06.008. Epub 2018 Jul 20. Am J Pathol. 2018. PMID: 30031728 Free article.
190 results